AJP - Regulatory, Integrative and Comparative Physiology, Vol 235, Issue 1 93-R98, Copyright © 1978 by American Physiological Society
Calibrating compartmental models of neurons
D. H. Perkel and B. Mulloney
Numerical parameters for a compartmental model of a neuron can be chosen to
conform both to the neuron's structure and to its measured steady-state
electrical properties. A systematic procedure for assigning parameters is
described that makes use of the matrix of coefficients of the set of
differential equations that embodies the compartmental model. The inverse
of this matrix furnishes input resistances and voltage attenuation factors
for the model, and an interactive modification of the original matrix and
its inverse may be used to fit the model to anatomic and electrical
measurements.
