AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 238: R306-R310, 1980;
0363-6119/80 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Regoeczi, E.
Right arrow Articles by Hatton, M. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Regoeczi, E.
Right arrow Articles by Hatton, M. W.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 238, Issue 5 306-R310, Copyright © 1980 by American Physiological Society

ARTICLES

Transferrin catabolism in mammalian species of different body sizes

E. Regoeczi and M. W. Hatton

Turnover of transferrin was measured in 62 mammals from 11 species (baboon, dog, goat, guinea pig, man, mouse, pig, rabbit, rat, rhesus monkey, and sheep) using iodinelabeled transferrin of homologous and/or heterologous origin. Protein turnover was determined either from the plasma protein-bound radioactivity curves or from the slopes of total body radiation. The volume of transferrin pool, expressed as equivalent milliliters of plasma, turned over per day correlated closely with species size (r = +0.977). Using the parabolic equation, y = axb, the constants for the relationship between body weight (x) and transferrin turnover (y) were a, 22.845; and b, 0.68. However, species of comparable weights with deviating transferrin turnovers do exist within the boundaries of this relationship. From a limited number of serum transferrin estimations in all species except for rhesus, six species appeared to have transferrin concentrations in a broad middle range (2.5-3.5 mg/ml). By comparison, dog and guinea pig had markedly lower, and pig and rat had markedly higher, serum transferrin concentrations.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
J. Kim, C. L. Bronson, W. L. Hayton, M. D. Radmacher, D. C. Roopenian, J. M. Robinson, and C. L. Anderson
Albumin turnover: FcRn-mediated recycling saves as much albumin from degradation as the liver produces
Am J Physiol Gastrointest Liver Physiol, February 1, 2006; 290(2): G352 - G360.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online