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Am J Physiol Regul Integr Comp Physiol 240: R120-R129, 1981;
0363-6119/81 $5.00
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AJP - Regulatory, Integrative and Comparative Physiology, Vol 240, Issue 3 120-R129, Copyright © 1981 by American Physiological Society

ARTICLES

Modeling and identification of metabolic systems

E. R. Carson, C. Cobelli and L. Finkelstein

Introductory principles of physiological systems analysis by computer simulation or computation are introduced. The problems of model formulation, identification, and validation are examined. Selected guidelines for successful modeling are suggested, and examples of such applications in the field of endocrinology and metabolism are given.




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