|
|
||||||||
AJP - Regulatory, Integrative and Comparative Physiology, Vol 241, Issue 3 158-R162, Copyright © 1981 by American Physiological Society
ARTICLES |
K. Yamasaki and M. C. Lico
Unilateral microinjection of serotonin (5-HT) into the solitary tract nucleus (STN) increased the amplitude of all electroencephalographic (EEG) waves ipsilateral to the site of injection. Unilateral STN blockage by lidocaine blocked the ipsilateral effect of 5-HT. Unilateral lesion of the area postrema (AP) increased the amplitude of the ipsilateral EEG in response to 5-HT stimulation of the obex. In contrast, unilateral lesion of both AP and STN decreased the amplitude of the ipsilateral EEG response to 5-HT. The data show that the STN is critically involved in 5-HT synchronizing mechanism and that the AP may have an inhibitory tonic effect on the STN.
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |