AJP - Regu AJP: Lung Cellular and Molecular Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 241: R286-R292, 1981;
0363-6119/81 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kostreva, D. R.
Right arrow Articles by Kampine, J. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kostreva, D. R.
Right arrow Articles by Kampine, J. P.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 241, Issue 5 286-R292, Copyright © 1981 by American Physiological Society

ARTICLES

Reflex effects of renal afferents on the heart and kidney

D. R. Kostreva, J. L. Seagard, A. Castaner and J. P. Kampine

The reflex effects of renal afferents on the heart and kidney were studied in dogs anesthetized with pentobarbital sodium. Renal afferent and efferent nerve activity recorded from the renal nerves during occlusion of a single renal vein resulted in increases in nontonically firing renal afferent activity and decreases in tonically firing afferent activity. Renal efferent nerve activity from the contralateral kidney was always inhibited during single renal vein occlusion. This decrease in nerve activity was associated with a decrease in renal vascular resistance. Denervation of the congested kidney eliminated the reflex changes in renal vascular resistance. Cardiopulmonary sympathetic efferent nerve activity from the ansae subclavia was always reflexly inhibited by single renal vein occlusion. Although heart rate and left ventricular contractile force were not altered during renal vein occlusion, right ventricular contractile force decreased by -6 to -25%. This reflex decrease in contractile force was eliminated by denervation of the congested kidney. These studies demonstrate that renal afferents, activated by increases in renal venous pressure, can reflexly inhibit contralateral renal and cardiopulmonary sympathetic efferent nerve activity, decrease contralateral renal vascular resistance, and decrease right ventricular contractile force, without altering heart rate.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
K. Shimizu, K. Matsukawa, J. Murata, H. Tsuchimochi, and I. Ninomiya
Partial renal ischemia elicits heterogeneous control of renal sympathetic nerve activity to ischemic and nonischemic regions of the kidney
Am J Physiol Regulatory Integrative Comp Physiol, February 1, 2006; 290(2): R322 - R330.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online