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Am J Physiol Regul Integr Comp Physiol 242: R421-R422, 1982;
0363-6119/82 $5.00
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AJP - Regulatory, Integrative and Comparative Physiology, Vol 242, Issue 5 421-R422, Copyright © 1982 by American Physiological Society

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Comment on "Parameter and structural identifiability concepts and ambiguities: a critical review and analysis"

K. R. Godfrey

Identifiability of a model for the glucose tolerance test, considered by Cobelli and DiStefano [Am. J. Physiol. 239 (Regulatory Integrative Comp. Physiol. 8): R7-R24, 1980], is shown to depend on the shape of the external perturbation. For systems with two or more inputs applied simultaneously, it is essential in Laplace transform identifiability analysis to examine the Laplace transform(s) of the observation(s) rather than the individual transfer functions, which are not measurable separately.




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