AJP - Regulatory, Integrative and Comparative Physiology, Vol 243, Issue 3 193-R204, Copyright © 1982 by American Physiological Society
Circadian timing of sleepiness in man and woman
A. T. Winfree
Men and women living contentedly in long-term isolation from the usual
time-of-day cues have revealed surprising new regularities about the timing
of human sleep/wake alternations. Contemporary effort to ferret out and
articulate these regularities in quantitative terms lead to a diversity of
mathematical models. If these eventually acquire predictive competence then
we may expect practical improvements of therapy for insomnia, jet lag, and
some kinds of psychiatric depression.
