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Am J Physiol Regul Integr Comp Physiol 243: R424-R432, 1982;
0363-6119/82 $5.00
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AJP - Regulatory, Integrative and Comparative Physiology, Vol 243, Issue 3 424-R432, Copyright © 1982 by American Physiological Society

ARTICLES

A new approach to compartmental analysis

M. H. Sherif

When recirculation of compounds and/or mixing transients are appreciable, traditional compartment analysis can lead to erroneous results. In this paper, a novel approach that overcomes many of these difficulties is presented. It unifies classical compartment analysis and indicator-dilution theory. It is conceptually simple and can be easily extended to many situations. Several examples for the case of a single compartment demonstrate the superiority of the suggested model to more traditional approaches.




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