AJP - Regulatory, Integrative and Comparative Physiology, Vol 245, Issue 1 110-R116, Copyright © 1983 by American Physiological Society
Forearm blood flow and metabolism during stylized and unstylized states of decreased activation
R. Jevning, A. F. Wilson, J. P. O'Halloran and R. N. Walsh
We have measured forearm oxygen consumption and blood flow changes during
two wakeful rest behaviors. We have observed acute reduction of forearm
respiration (28%) during an acute stylized rest state (TM) and a
nonsignificant small decline (11%) during unstylized ordinary eyes-closed
rest. These changes were not associated with significant change of forearm
blood flow or glycolytic metabolism. Hence, forearm oxygen consumption
decline was due almost solely to decreased rate of oxygen extraction. Small
variation of forearm blood flow implies that little of the previous
findings of increased nonrenal, nonhepatic circulation during TM or
increased nonrenal circulation during ordinary rest can be accounted for by
altered muscle blood flow, which therefore is consistent with possible
increased cerebral blood flow. However, reduced muscle metabolism was a
likely contributor to the forearm metabolic decline. The lack of coupling
between metabolic and blood flow changes during TM indicates limitation of
obligatory coupling between cardiovascular and metabolic function in the
rest state of TM.
