AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 245: R83-R90, 1983;
0363-6119/83 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lind, R. W.
Right arrow Articles by Johnson, A. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lind, R. W.
Right arrow Articles by Johnson, A. K.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 245, Issue 1 83-R90, Copyright © 1983 by American Physiological Society

ARTICLES

A further characterization of the effects of AV3V lesions on ingestive behavior

R. W. Lind and A. K. Johnson

Rats prescreened for responses to dipsogens received anteroventral third cerebral ventricular (AV3V) or sham lesions (ether anesthesia). Many known effects of AV3V lesions were observed, and new findings include a failure to drink adequately in response to polyethylene glycol (PEG) and water deprivation (regardless of responses to other dipsogens) and abnormally high levels of water intake during food deprivation. The groups did not differ in the osmotic suppression of deprivation-induced feeding. Drinking responses to angiotensin, isoproterenol, and PEG were highly intercorrelated in the experimental animals, perhaps due to destruction of an angiotensin-related substrate. Five months after surgery, rats with lesions were hyperphagic and hyperdipsic per gram of body weight, but actually ate a smaller amount of food than control rats, and absolute levels of water intake did not differ. The range of amount of daily water intake, but not food intake, was significantly greater in the experimental rats. These findings suggest that lower levels of neural organization mediate fluid balance in rats with AV3V lesions.


This article has been cited by other articles:


Home page
 Physiol. Rev.Home page
J. ANTUNES-RODRIGUES, M. DE CASTRO, L. L. K. ELIAS, M. M. VALENCA, and S. M. McCANN
Neuroendocrine Control of Body Fluid Metabolism
Physiol Rev, January 1, 2004; 84(1): 169 - 208.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online