AJP - Regulatory, Integrative and Comparative Physiology, Vol 245, Issue 2 151-R153, Copyright © 1983 by American Physiological Society
Interhemispheric coupling coefficients: sex differences in brain neurochemistry
V. H. Denenberg and G. D. Rosen
Previously it was shown that the presence of a significant positive
correlation between measures of the right and left hemispheres may be taken
as evidence of a negative feedback loop linking the hemispheres [Denenberg,
V. H. Am. J. Physiol. 238 (Regulatory Integrative Comp. Physiol. 7):
R3-R13, 1980]. Such a finding is indicative of a different form of brain
organization, compared with brains that lack this correlation. The purpose
of this paper was to compare male and female rats with respect to
correlations of left- and right-sided values for a set of brain
neurochemicals. The variable of sex was chosen because there are ample data
showing differences in brain organization. Neurochemical correlations in
the nucleus accumbens and the striatum did not demonstrate any sex
difference, but differences were found in neocortex: female rats had
significantly greater hemispheric correlations than males for dopamine,
5-hydroxyindoleacetic acid, and serotonin turnover.
