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Am J Physiol Regul Integr Comp Physiol 246: R114-R121, 1984;
0363-6119/84 $5.00
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AJP - Regulatory, Integrative and Comparative Physiology, Vol 246, Issue 1 114-R121, Copyright © 1984 by American Physiological Society

ARTICLES

A model eliciting transient responses

E. B. Ekblad and V. Licko

A simple parametrically controlled chemical transformation scheme is used to exemplify a model with transient response to sustained stimulation. More complicated schemes are also discussed. Analyses of three experimental examples are given: short-circuit current changes in toad bladder exposed to adenosine 3',5'-cyclic monophosphate (cAMP) stimulation; histamine secretion in acetylcholine-stimulated frog gastric mucosa; and cAMP dynamics, expressed in terms of adenylate cyclase dynamics, in histamine-stimulated frog gastric mucosa. The model responds primarily to the changes of the stimulator level, although it is not a model with derivative control.




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