AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 250: R728-R732, 1986;
0363-6119/86 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Warner, A. E.
Right arrow Articles by Brain, J. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Warner, A. E.
Right arrow Articles by Brain, J. D.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 250, Issue 4 728-R732, Copyright © 1986 by American Physiological Society

ARTICLES

Intravascular pulmonary macrophages: a novel cell removes particles from blood

A. E. Warner and J. D. Brain

Clearance of radiolabeled gold colloid from the blood and relative organ distribution of retained colloid and magnetic iron oxide particles were compared between rats and calves. When unanesthetized calves 1 wk of age were injected intravenously with these two particle types, uptake was predominantly pulmonary. In contrast, in the rat there was overwhelming hepatic uptake. Similar pulmonary localization of injected particulate material was found in adult goats. When lung tissue was examined by electron microscopy, injected iron oxide was found within intravascular pulmonary macrophages. The mononuclear phagocyte system removes particulate material of both exogenous and endogenous origin from the circulation; hepatic and splenic uptake of such material usually predominates. We found that, unlike the species previously studied, ruminants have actively phagocytic cells within the pulmonary vasculature. Thus pulmonary intravascular macrophages constitute an important part of the mononuclear phagocyte system in some species.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
C. Feleder, Z. Li, V. Perlik, A. Evans, and C. M. Blatteis
The spleen modulates the febrile response of guinea pigs to LPS
Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2003; 284(6): R1466 - R1476.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online