AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 257: R29-R36, 1989;
0363-6119/89 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Janssen, B. J.
Right arrow Articles by Smits, J. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Janssen, B. J.
Right arrow Articles by Smits, J. F.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 257, Issue 1 29-R36, Copyright © 1989 by American Physiological Society

ARTICLES

Hemodynamic effects of activation of renal and mesenteric sensory nerves in rats

B. J. Janssen, H. van Essen, H. A. Struyker Boudier and J. F. Smits
Department of Pharmacology, University of Limburg, Maastricht, The Netherlands.

Afferent nerves from the kidney and mesentery reflexly influence the cardiovascular system when activated. To examine the specificity of these reflexes, comparisons were made of the regional hemodynamic responses elicited by intra-arterial infusion of various agents into the renal (ir) and mesenteric (im) circulation. Experiments were performed in conscious rats, chronically instrumented with Doppler flow probes. Local ir as well as im infusions of bradykinin caused a hemodynamic reflex pattern characterized by a dose-dependent increase in arterial pressure, heart rate, and resistance in the renal and mesenteric vascular beds, whereas hindquarter resistance did not change. Similar hemodynamic reflex patterns were evoked by ir and im infusions of adenosine and 5-hydroxytryptamine. Thus neither application of different chemicals nor their route of infusion resulted in qualitatively different hemodynamic reflex patterns. This suggests that afferent nerve fibers from the kidney and mesentery share a common physiological function.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
D. A. Liem, P. D. Verdouw, H. Ploeg, S. Kazim, and D. J. Duncker
Sites of action of adenosine in interorgan preconditioning of the heart
Am J Physiol Heart Circ Physiol, July 1, 2002; 283(1): H29 - H37.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
R. G. Schoemaker and C. L. van Heijningen
Bradykinin mediates cardiac preconditioning at a distance
Am J Physiol Heart Circ Physiol, May 1, 2000; 278(5): H1571 - H1576.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
S. Shigematsu, S. Ishida, D. C. Gute, and R. J. Korthuis
Concentration-dependent effects of bradykinin on leukocyte recruitment and venular hemodynamics in rat mesentery
Am J Physiol Heart Circ Physiol, July 1, 1999; 277(1): H152 - H160.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
B. C.G. Gho, R. G. Schoemaker, M. A. van den Doel, D. J. Duncker, and P. D. Verdouw
Myocardial Protection by Brief Ischemia in Noncardiac Tissue
Circulation, November 1, 1996; 94(9): 2193 - 2200.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online