AJP - Regu AJP: Renal Physiology
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Am J Physiol Regul Integr Comp Physiol 257: R668-R671, 1989;
0363-6119/89 $5.00
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AJP - Regulatory, Integrative and Comparative Physiology, Vol 257, Issue 3 668-R671, Copyright © 1989 by American Physiological Society

ARTICLES

Simple and inexpensive delivery of halogenated inhalation anesthetics to rodents

R. T. Henry and R. Casto
Department of Pharmacology, University of California, San Diego, La Jolla, 90293.

Halogenated inhalation anesthetics offer several advantages over injectable anesthetics for small-animal surgery. Benefits include rapid induction, easy adjustment of anesthetic depth, and a short period of recovery. Although the cost of most inhalation anesthetics is low, present delivery systems are often prohibitively expensive for rodent uses. This report describes a low-cost, portable system that can be used with halothane or isoflurane for general surgery or stereotaxic applications with or without intubation. Also included is a description of rodent nose cones for both general surgery and stereotaxic surgery that allow for simple evacuation of waste gases.




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