| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
AJP - Regulatory, Integrative and Comparative Physiology, Vol 260, Issue 6 1082-R1088, Copyright © 1991 by American Physiological Society
ARTICLES |
E. M. Stricker, E. Thiels and J. G. Verbalis
Department of Behavioral Neuroscience, University of Pittsburgh, Pennsylvania 15260.
Little sodium appetite is observed when rats are deprived of dietary sodium for several days, presumably because aldosterone secretion minimizes renal sodium losses. However, the present studies indicate that when sodium deprivation is extended to 8 days, a spontaneous sodium appetite results that far exceeds urinary sodium losses during the deprivation period; indeed, adult male rats drank as much 0.5 M NaCl solution as rats ever have been reported to drink rapidly. In contrast, female rats drank much less saline after 8 days of sodium deprivation. Because of this sexual dimorphism in sodium appetite, we also studied NaCl intake in gonadectomized rats after 8 days of sodium deprivation. Both male and female gonadectomized rats drank comparable amounts of saline as intact male rats, but they consumed much less when treated with physiological amounts of estrogen during the sodium-deprivation period. These results indicate that a robust appetite for NaCl can be produced in rats by prolonged sodium deprivation and that estrogen can blunt the induced sodium appetite.
This article has been cited by other articles:
|
|
 |
|
  A. S. Mecawi, A. Lepletier, I. G. Araujo, F. V. Fonseca, and L. C. Reis Oestrogenic influence on brain AT1 receptor signalling on the thirst and sodium appetite in osmotically stimulated and sodium-depleted female rats Exp Physiol, August 1, 2008; 93(8): 1002 - 1010. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. Geerling and A. D. Loewy Central regulation of sodium appetite Exp Physiol, February 1, 2008; 93(2): 177 - 209. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. M. Stricker, M. A. Bushey, M. L. Hoffmann, M. McGhee, A. M. Cason, and J. C. Smith Inhibition of NaCl appetite when DOCA-treated rats drink saline Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2007; 292(1): R652 - R662. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Kensicki, G. Dunphy, and D. Ely Estradiol increases salt intake in female normotensive and hypertensive rats J Appl Physiol, August 1, 2002; 93(2): 479 - 483. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Amico, M. Morris, and R. R. Vollmer Mice deficient in oxytocin manifest increased saline consumption following overnight fluid deprivation Am J Physiol Regulatory Integrative Comp Physiol, November 1, 2001; 281(5): R1368 - R1373. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. McCaughey and T. R. Scott Rapid induction of sodium appetite modifies taste-evoked activity in the rat nucleus of the solitary tract Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2000; 279(3): R1121 - R1131. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. S. Curtis, W. Huang, A. F. Sved, J. G. Verbalis, and E. M. Stricker Impaired osmoregulatory responses in rats with area postrema lesions Am J Physiol Regulatory Integrative Comp Physiol, July 1, 1999; 277(1): R209 - R219. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. T. FITZSIMONS Angiotensin, Thirst, and Sodium Appetite Physiol Rev, July 1, 1998; 78(3): 583 - 686. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
