AJP - Regulatory, Integrative and Comparative Physiology, Vol 263, Issue 2 339-R347, Copyright © 1992 by American Physiological Society

ARTICLES

Weakness of short-term synchronization among respiratory nerve activities during fictive vomiting

M. I. Cohen, A. D. Miller, R. Barnhardt and C. F. Shaw
Department of Physiology and Biophysics, Albert Einstein College of Medicine, New York 10461.

In decerebrate, paralyzed cats, phrenic (PHR) and lumbar abdominal (ABD) nerve discharges during both neural respiration and fictive vomiting (FV) were subjected to spectral and coherence analyses. During respiration, PHR discharge exhibited high-frequency oscillation (HFO), manifested as a narrow spectral peak (range 57-90 Hz) in autospectra and left-right coherence spectra. During FV, the following occurred: 1) the HFO peak disappeared and was replaced by a broad peak with higher modal frequency (range 84-120 Hz), indicating elimination of inputs from the medullary inspiratory pattern generator. 2) Left-right PHR coherence spectra had no distinct peaks, indicating that correlations between opposite PHR discharges were now not frequency specific. 3) Although ABD and PHR autospectra were similar, PHR-ABD coherences were near zero, indicating lack of common inputs on a short time scale. 4) Nonzero coherences between ABD nerves were confined to ipsilateral pairs. Thus coherence analysis indicates that the outputs of the vomiting pattern generator are temporally dispersed on a short time scale and are not necessarily common to different motoneuron populations.

This article has been cited by other articles:

				K. Nakazawa, A. R. Granata, and M. I. Cohen Synchronized Fast Rhythms in Inspiratory and Expiratory Nerve Discharges During Fictive Vocalization J Neurophysiol, March 1, 2000; 83(3): 1415 - 1425. [Abstract] [Full Text] [PDF]