AJP - Regu Information on EB 2010
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 263: R524-R528, 1992;
0363-6119/92 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Harada, S.
Right arrow Articles by Takeshita, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Harada, S.
Right arrow Articles by Takeshita, A.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 263, Issue 3 524-R528, Copyright © 1992 by American Physiological Society

ARTICLES

Arterial baroreflex dynamics in normotensive and spontaneously hypertensive rats

S. Harada, T. Imaizumi, S. Ando, Y. Hirooka, K. Sunagawa and A. Takeshita
Research Institute of Angiocardiology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

To investigate dynamic or frequency-dependent characteristics of arterial baroreflex control of efferent sympathetic nerve activity in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY), we assessed the transfer function from aortic pressure (AP) to renal sympathetic nerve activity (RSNA) using a "white-noise technique." In pentobarbital sodium-anesthetized rats, we recorded RSNA as the output, while AP was randomly perturbed to impose input pressure changes with broad frequencies. We calculated the transfer function from AP to RSNA over the frequency range of 0.01-5 Hz through the spectral analysis of the input and output. The results indicated that the gain, phase shift, and coherence of the transfer function for SHR and for WKY were similar and statistically indistinguishable. The gain was relatively constant below 0.05 Hz but increased steadily by fivefold as frequency increased in the frequency range of 0.05-0.8 Hz. The phase was out of phase where coherence was high. The coherence was high (greater than 0.5) in the frequency range of 0.04-0.8 and 1.00-1.03 Hz but was low in other frequencies. These results suggest that dynamic or frequency-dependent characteristics of arterial baroreflex control of RSNA were not altered in SHR as compared with WKY.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
H. C. Salgado, A. R. Barale, J. A. Castania, B. H. Machado, M. W. Chapleau, and R. Fazan Jr.
Baroreflex responses to electrical stimulation of aortic depressor nerve in conscious SHR
Am J Physiol Heart Circ Physiol, January 1, 2007; 292(1): H593 - H600.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
J. T. Potts, K. P. McKeown, and A. A. Shoukas
Reduction in arterial compliance alters carotid baroreflex control of cardiac output in a model of hypertension
Am J Physiol Heart Circ Physiol, April 1, 1998; 274(4): H1121 - H1131.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online