AJP - Regu AJP citation statistics
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 266: R510-R517, 1994;
0363-6119/94 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sollars, S. I.
Right arrow Articles by Bernstein, I. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sollars, S. I.
Right arrow Articles by Bernstein, I. L.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 266, Issue 2 510-R517, Copyright © 1994 by American Physiological Society

ARTICLES

Gustatory deafferentation and desalivation: effects on NaCl preference of Fischer 344 rats

S. I. Sollars and I. L. Bernstein
Department of Psychology, University of Washington, Seattle 98195.

The chorda tympani nerve (CT) appears to be particularly responsive to NaCl stimulation of the tongue. However, in most strains of rat, bilateral transection of the CT (CTX) results in little alteration of salt preference. The Fischer 344 (F344) strain of rat is unusual in its lack of preference for any concentration of salt. We recently reported a dramatic change from aversion to preference for salt in F344 rats after CTX. The present studies further explored this alteration in salt preference of F344 rats with an expanded range of NaCl concentrations. Additionally, the specificity of the CT in mediating F344 salt aversion was examined by testing NaCl preference after glossopharyngeal nerve (GL) transections, combined CT and GL deafferentation, and partial desalivation. Comparison with Wistar rats revealed that salt preference of F344 CTX rats followed a typical preference/aversion pattern across a range of NaCl concentrations. Studies of GL section, either alone or combined with CT sectioning, indicated that F344 rats' aversion was dependent on the integrity of the CT and not the GL. Removal of sublingual and submaxillary salivary glands did not lead to preference changes similar to those after CTX, indicating that the effects of CTX are not secondary to desalivation. Overall, the findings point to signals from the CT as playing a primary role in the NaCl aversion displayed by the intact F344 rat.


This article has been cited by other articles:


Home page
 Chem SensesHome page
S. N.D.A. Clarke, M. T. Koh, and I. L. Bernstein
NaCl Detection Thresholds: Comparison of Fischer 344 and Wistar rats
Chem Senses, April 1, 2001; 26(3): 253 - 257.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
M. D. Brot, C. H. Watson, and I. L. Bernstein
Amiloride-sensitive signals and NaCl preference and appetite: a lick-rate analysis
Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2000; 279(4): R1403 - R1411.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online