| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
AJP - Regulatory, Integrative and Comparative Physiology, Vol 269, Issue 5 1085-R1092, Copyright © 1995 by American Physiological Society
ARTICLES |
F. S. Kraly, Y. M. Kim, L. M. Dunham and R. A. Tribuzio
Department of Psychology, Colgate University, Hamilton, New York 13346, USA.
Drinking after intragastric hypertonic solutions was examined to determine whether increased plasma osmolality always accompanied initiation of drinking. A 2-ml infusion through a gastric catheter was the beginning of tests in Sprague-Dawley male rats. Latency to drink was shorter and 1-h water intake was greater for increasing concentrations of NaCl (600, 1,200, and 1,800 mosmol/kg) compared with baseline (290 mosmol/kg). Although 600, 900, or 1,200 mosmol/kg NaCl elicited drinking, such infusions failed to change systemic plasma osmolality, and 900 mosmol/kg also failed to change plasma sodium, protein, renin activity, or packed cell volume at the initiation of drinking. Intragastric 900 mosmol/kg sodium bicarbonate, sodium isethionate, potassium chloride, lithium chloride, and mannitol differentially increased water intake. Total subdiaphragmatic vagotomy abolished drinking elicited by intragastric NaCl; selective gastric or hepatic vagotomy attenuated intake under some conditions. These results support the hypothesis of a vagally mediated, gastrointestinal and/or hepatic-portal, osmosensitive mechanism for initiation of drinking in advance of postprandial increases in systemic osmolality.
This article has been cited by other articles:
|
|
 |
|
  A. Godino, L. A. De Luca Jr., J. Antunes-Rodrigues, and L. Vivas Oxytocinergic and serotonergic systems involvement in sodium intake regulation: satiety or hypertonicity markers? Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2007; 293(3): R1027 - R1036. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Smith, K. S. Curtis, J. C. Smith, and E. M. Stricker Presystemic influences on thirst, salt appetite, and vasopressin secretion in the hypovolemic rat Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2007; 292(5): R2089 - R2099. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. M. Stricker, M. A. Bushey, M. L. Hoffmann, M. McGhee, A. M. Cason, and J. C. Smith Inhibition of NaCl appetite when DOCA-treated rats drink saline Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2007; 292(1): R652 - R662. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. L. Brooks, K. L. Freeman, and Y. Qi Time course of synergistic interaction between DOCA and salt on blood pressure: roles of vasopressin and hepatic osmoreceptors Am J Physiol Regulatory Integrative Comp Physiol, December 1, 2006; 291(6): R1825 - R1834. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Manesh, M. L. Hoffmann, and E. M. Stricker Water ingestion by rats fed a high-salt diet may be mediated, in part, by visceral osmoreceptors Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2006; 290(6): R1742 - R1749. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. M. Stricker and M. L. Hoffmann Inhibition of vasopressin secretion when dehydrated rats drink water Am J Physiol Regulatory Integrative Comp Physiol, November 1, 2005; 289(5): R1238 - R1243. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Rinaman, R. R. Vollmer, J. Karam, D. Phillips, X. Li, and J. A. Amico Dehydration anorexia is attenuated in oxytocin-deficient mice Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2005; 288(6): R1791 - R1799. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Freece, J. E. Van Bebber, D. K. Zierath, and D. A. Fitts Subfornical organ disconnection alters Fos expression in the lamina terminalis, supraoptic nucleus, and area postrema after intragastric hypertonic NaCl Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2005; 288(4): R947 - R955. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. S. Curtis, E. G. Krause, D. L. Wong, and R. J. Contreras Gestational and early postnatal dietary NaCl levels affect NaCl intake, but not stimulated water intake, by adult rats Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2004; 286(6): R1043 - R1050. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. H. M. Schoorlemmer and M. D. Evered Reduced feeding during water deprivation depends on hydration of the gut Am J Physiol Regulatory Integrative Comp Physiol, November 1, 2002; 283(5): R1061 - R1069. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. M. Stricker, J. B. Callahan, W. Huang, and A. F. Sved Early osmoregulatory stimulation of neurohypophyseal hormone secretion and thirst after gastric NaCl loads Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2002; 282(6): R1710 - R1717. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. M. Starbuck and D. A. Fitts Influence of the subfornical organ on meal-associated drinking in rats Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2001; 280(3): R669 - R677. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Huang, A. F. Sved, and E. M. Stricker Water ingestion provides an early signal inhibiting osmotically stimulated vasopressin secretion in rats Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2000; 279(3): R756 - R760. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Fang, S. H. Carlson, N. Peng, and J. M. Wyss Circadian rhythm of plasma sodium is disrupted in spontaneously hypertensive rats fed a high-NaCl diet Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2000; 278(6): R1490 - R1495. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. H. Carlson and J. M. Wyss Hepatic denervation does not affect plasma vasopressin response to intragastric hypertonic saline in conscious rats Am J Physiol Endocrinol Metab, July 1, 1999; 277(1): E161 - E167. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. H. Carlson, J. P. Collister, and J. W. Osborn The area postrema modulates hypothalamic Fos responses to intragastric hypertonic saline in conscious rats Am J Physiol Regulatory Integrative Comp Physiol, December 1, 1998; 275(6): R1921 - R1927. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. H. Carlson and J. W. Osborn Splanchnic and vagal denervation attenuate central Fos but not AVP responses to intragastric salt in rats Am J Physiol Regulatory Integrative Comp Physiol, May 1, 1998; 274(5): R1243 - R1252. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
