AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 269: R1441-R1447, 1995;
0363-6119/95 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Toth, L. A.
Right arrow Articles by Krueger, J. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Toth, L. A.
Right arrow Articles by Krueger, J. M.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 269, Issue 6 1441-R1447, Copyright © 1995 by American Physiological Society

ARTICLES

Lighting conditions alter Candida albicans-induced sleep responses in rabbits

L. A. Toth and J. M. Krueger
Department of Comparative Medicine, University of Tennessee, Memphis 38163, USA.

To evaluate the influence of light on sleep patterns after microbial challenge, we studied rabbits housed in 12:12-h light-dark (LD), constant light (LL), or constant darkness (DD) before and after intravenous Candida albicans inoculation. Compared with the LD group, uninoculated LL rabbits sporadically increased slow-wave sleep and delta-wave amplitudes during the circadian period previously associated with the dark phase. In contrast, uninfected DD rabbits showed reduced sleep during the circadian period previously associated with the light phase. Inoculation of LD rabbits with Candida approximately 2 h after light onset increased slow-wave sleep and delta-wave amplitudes during hours 4-8 postinoculation and reduced these parameters during hours 20-46. In contrast, Candida-inoculated LL rabbits demonstrated increased slow-wave sleep for up to 28 h after inoculation, with little subsequent reduction; delta-wave amplitudes were similar to those of LD rabbits. Candida-inoculated DD rabbits demonstrated attenuated increases in slow-wave sleep and delta-wave amplitudes, but the suppression phase was not altered. We conclude that lighting conditions modulate microbially induced sleep alterations.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
K. A. Jhaveri, V. Ramkumar, R. A. Trammell, and L. A. Toth
Spontaneous, homeostatic, and inflammation-induced sleep in NF-{kappa}B p50 knockout mice
Am J Physiol Regulatory Integrative Comp Physiol, November 1, 2006; 291(5): R1516 - R1526.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
T. Yasuda, K. Yasuda, R. A. Brown, and J. M. Krueger
State-dependent effects of light-dark cycle on somatosensory and visual cortex EEG in rats
Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2005; 289(4): R1083 - R1089.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online