| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
AJP - Regulatory, Integrative and Comparative Physiology, Vol 270, Issue 2 420-R426, Copyright © 1996 by American Physiological Society
ARTICLES |
J. R. Halliwill, J. A. Taylor, T. D. Hartwig and D. L. Eckberg
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA.
The occurrence of a sustained vasodilation and hypotension after acute, dynamic exercise suggests that exercise may alter arterial baroreflex mechanisms. Therefore, we assessed systemic hemodynamics, baroreflex regulation of heart rate, and cardiac vagal tone after 60 min of cycling at 60% peak oxygen consumption in 12 healthy, untrained men and women (ages 21-28 yr). We derived sigmoidal carotid-cardiac baroreflex relations by measurement of R-R interval changes induced by ramped, stepwise, R-wave-triggered changes in external neck pressure from 40 to -65 mmHg. We estimated tonic cardiac vagal control with power spectral analysis of R-R interval variability in the respiratory frequency band (0.2-0.3 Hz) during frequency- and tidal volume-controlled breathing. Both mean arterial pressure and total peripheral resistance were reduced postexercise [pressure: from 86 +/- 2 (mean +/- SE) to 81 +/- 2 mmHg; resistance: from 23 +/- 2 to 16 +/- 1 units; both P < 0.05]. Cardiac output was increased postexercise (from 3.9 +/- 0.3 to 5.5 +/- 0.5 l/min, P < 0.05). Both slope and range of the carotid-cardiac baroreflex relation were increased postexercise (slope: from 4.7 +/- 0.7 to 6.1 +/- 0.9 ms/mmHg; range: from 186 +/- 23 to 238 +/- 30 ms, P < 0.05). Respiratory R-R interval variability (cardiac vagal tone) was not changed at any time after exercise, whereas heart rate and plasma norepinephrine levels were elevated. Thus moderate-intensity, dynamic exercise increases heart rate and cardiac output, reduces peripheral vascular resistance, and augments baroreflex responsiveness. Our data suggest that augmented baroreflex heart rate gain restrains rather than contributes to postexercise hypotension, which appears to be mediated predominately by vasodilation.
This article has been cited by other articles:
|
|
 |
|
  G. P. Kenny and O. Jay Sex differences in postexercise esophageal and muscle tissue temperature response Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2007; 292(4): R1632 - R1640. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. Lynn, J. L. McCord, and J. R. Halliwill Effects of the menstrual cycle and sex on postexercise hemodynamics Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2007; 292(3): R1260 - R1270. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. McCord and J. R. Halliwill H1 and H2 receptors mediate postexercise hyperemia in sedentary and endurance exercise-trained men and women J Appl Physiol, December 1, 2006; 101(6): 1693 - 1701. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. McCord, J. M. Beasley, and J. R. Halliwill H2-receptor-mediated vasodilation contributes to postexercise hypotension J Appl Physiol, January 1, 2006; 100(1): 67 - 75. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. T. Williams, M. P. Pricher, and J. R. Halliwill Is postexercise hypotension related to excess postexercise oxygen consumption through changes in leg blood flow? J Appl Physiol, April 1, 2005; 98(4): 1463 - 1468. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M Lockwood, B. W Wilkins, and J. R Halliwill H1 receptor-mediated vasodilatation contributes to postexercise hypotension J. Physiol., March 1, 2005; 563(2): 633 - 642. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Lockwood, M. P. Pricher, B. W. Wilkins, L. A. Holowatz, and J. R. Halliwill Postexercise hypotension is not explained by a prostaglandin-dependent peripheral vasodilation J Appl Physiol, February 1, 2005; 98(2): 447 - 453. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. P. Pricher, L. A. Holowatz, J. T. Williams, J. M. Lockwood, and J. R. Halliwill Regional hemodynamics during postexercise hypotension. I. Splanchnic and renal circulations J Appl Physiol, December 1, 2004; 97(6): 2065 - 2070. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. W. Wilkins, C. T. Minson, and J. R. Halliwill Regional hemodynamics during postexercise hypotension. II. Cutaneous circulation J Appl Physiol, December 1, 2004; 97(6): 2071 - 2076. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. C. Ziegelstein Near-Syncope After Exercise JAMA, September 8, 2004; 292(10): 1221 - 1226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Laude, J.-L. Elghozi, A. Girard, E. Bellard, M. Bouhaddi, P. Castiglioni, C. Cerutti, A. Cividjian, M. Di Rienzo, J.-O. Fortrat, et al. Comparison of various techniques used to estimate spontaneous baroreflex sensitivity (the EuroBaVar study) Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2004; 286(1): R226 - R231. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. N. Senitko, N. Charkoudian, and J. R. Halliwill Influence of endurance exercise training status and gender on postexercise hypotension J Appl Physiol, June 1, 2002; 92(6): 2368 - 2374. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R. Halliwill, C. T. Minson, and M. J. Joyner Effect of systemic nitric oxide synthase inhibition on postexercise hypotension in humans J Appl Physiol, November 1, 2000; 89(5): 1830 - 1836. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. P. Chandler, D. W. Rodenbaugh, and S. E. DiCarlo Arterial baroreflex resetting mediates postexercise reductions in arterial pressure and heart rate Am J Physiol Heart Circ Physiol, November 1, 1998; 275(5): H1627 - H1634. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. P. Chandler and S. E. Dicarlo Sinoaortic denervation prevents postexercise reductions in arterial pressure and cardiac sympathetic tonus Am J Physiol Heart Circ Physiol, December 1, 1997; 273(6): H2738 - H2745. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
