| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
AJP - Regulatory, Integrative and Comparative Physiology, Vol 271, Issue 6 1759-R1769, Copyright © 1996 by American Physiological Society
ARTICLES |
B. N. Van Vliet, L. Hu, T. Scott, L. Chafe and J. P. Montani
Faculty of Medicine, Memorial University of Newfoundland, St. John's, Canada. bvliet@plato.ucs.mun.ca
We investigated cardiac morphometry 6 wk after sinoaortic baroreceptor denervation (SAD) in Long-Evans rats. SAD (n = 19) was associated with an 11% increase in the weight of the left ventricle (LV) plus septum (P < 0.001) and a 39% increase in that of the right ventricular (RV) free wall (P < 0.001), relative to sham-operated rats (n = 18). RV wall thickness was significantly increased in SAD animals, but there was no difference in the LV wall thickness and volumes of the RV and LV between groups. Constrictor responses to methoxamine and dilation responses to acetylcholine were assessed in an in vitro perfused mesenteric circulation preparation, but neither response was affected by SAD. Baroreceptor denervation was associated with marked and significant increases in the variability (2.8-fold) and daily peak (39 mmHg) levels of telemetered mean arterial pressure (MAP) and small (5%) but significant increases in the daily mean MAP level. Our results are consistent with an effect of increased MAP variability on ventricular weight but cannot rule out possible contributions from other mechanisms.
This article has been cited by other articles:
|
|
 |
|
  S.-J. Guild, C. J. Barrett, F. D. McBryde, B. N. Van Vliet, and S. C. Malpas Sampling of cardiovascular data; how often and how much? Am J Physiol Regulatory Integrative Comp Physiol, August 1, 2008; 295(2): R510 - R515. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Ayer, V. Antic, A. G. Dulloo, B. N. Van Vliet, and J.-P. Montani Hemodynamic consequences of chronic parasympathetic blockade with a peripheral muscarinic antagonist Am J Physiol Heart Circ Physiol, August 1, 2007; 293(2): H1265 - H1272. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. A. Cupples and B. Braam Assessment of renal autoregulation Am J Physiol Renal Physiol, April 1, 2007; 292(4): F1105 - F1123. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. J. Barrett, S.-J. Guild, R. Ramchandra, and S. C. Malpas Baroreceptor Denervation Prevents Sympathoinhibition During Angiotensin II-Induced Hypertension Hypertension, July 1, 2005; 46(1): 168 - 172. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. J. Barrett and S. C. Malpas Problems, possibilities, and pitfalls in studying the arterial baroreflexes' influence over long-term control of blood pressure Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2005; 288(4): R837 - R845. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. A. Lanfranchi and V. K Somers Arterial baroreflex function and cardiovascular variability: interactions and implications Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2002; 283(4): R815 - R826. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Narkiewicz, M. Winnicki, K. Schroeder, B. G. Phillips, M. Kato, E. Cwalina, and V. K. Somers Relationship Between Muscle Sympathetic Nerve Activity and Diurnal Blood Pressure Profile Hypertension, January 1, 2002; 39(1): 168 - 172. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. L.S. Pires, C. Barres, J. Sassard, and C. Julien Renal Blood Flow Dynamics and Arterial Pressure Lability in the Conscious Rat Hypertension, July 1, 2001; 38(1): 147 - 152. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Narkiewicz, N. Montano, C. Cogliati, P. J. H. van de Borne, M. E. Dyken, and V. K. Somers Altered Cardiovascular Variability in Obstructive Sleep Apnea Circulation, September 15, 1998; 98(11): 1071 - 1077. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
