| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
AJP - Regulatory, Integrative and Comparative Physiology, Vol 272, Issue 2 648-R655, Copyright © 1997 by American Physiological Society
ARTICLES |
M. R. Opp, L. A. Toth and E. A. Tolley
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston 77555, USA.
Slow-wave activity in the electroencephalogram is thought to reflect the depth or intensity of sleep. This hypothesis is primarily derived from studies of rats or humans. However, some characteristics of sleep of rabbits differ from those of rats or humans. To determine whether slow-wave activity (power density in the delta frequency band of 0.5-5.0 Hz) correlates with arousability in rabbits, we presented auditory stimuli (72-90 dB) to control or sleep-deprived animals during slow-wave sleep. The resulting behavioral responses, defined by changes in eye state and body posture, and the latency to return to sleep were used as measures of arousability. Behavioral responsiveness to auditory stimuli increased with increasing stimulus intensity in both control and sleep-deprived animals. Overall, however, sleep-deprived animals exhibited fewer postural changes and eye openings than did control rabbits. Sleep-deprived rabbits also more rapidly returned to sleep after the stimulus presentation than did control animals. Latency to return to sleep was correlated with delta power before stimulus presentation, but behavioral responsiveness was not. These data suggest that, in this rabbit model, delta power may not be predictive of behavioral arousability but may reflect sleep propensity.
This article has been cited by other articles:
|
|
 |
|
  E. Szentirmai, T. Yasuda, P. Taishi, M. Wang, L. Churchill, S. Bohnet, P. Magrath, B. Kacsoh, L. Jimenez, and J. M. Krueger Growth hormone-releasing hormone: cerebral cortical sleep-related EEG actions and expression Am J Physiol Regulatory Integrative Comp Physiol, August 1, 2007; 293(2): R922 - R930. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Yasuda, K. Yasuda, R. A. Brown, and J. M. Krueger State-dependent effects of light-dark cycle on somatosensory and visual cortex EEG in rats Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2005; 289(4): R1083 - R1089. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kushikata, T. Kubota, J. Fang, and J. M. Krueger Glial cell line-derived neurotrophic factor promotes sleep in rats and rabbits Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2001; 280(4): R1001 - R1006. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kubota, J. Fang, T. Kushikata, and J. M. Krueger Interleukin-13 and transforming growth factor-beta 1 inhibit spontaneous sleep in rabbits Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2000; 279(3): R786 - R792. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kushikata, J. Fang, and J. M. Krueger Brain-derived neurotrophic factor enhances spontaneous sleep in rats and rabbits Am J Physiol Regulatory Integrative Comp Physiol, May 1, 1999; 276(5): R1334 - R1338. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kushikata, J. Fang, Y. Wang, and J. M. Krueger Interleukin-4 inhibits spontaneous sleep in rabbits Am J Physiol Regulatory Integrative Comp Physiol, October 1, 1998; 275(4): R1185 - R1191. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kushikata, J. Fang, Z. Chen, Y. Wang, and J. M. Krueger Epidermal growth factor enhances spontaneous sleep in rabbits Am J Physiol Regulatory Integrative Comp Physiol, August 1, 1998; 275(2): R509 - R514. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
