AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 273: R554-R559, 1997;
0363-6119/97 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Monda, M.
Right arrow Articles by Viggiano, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Monda, M.
Right arrow Articles by Viggiano, A.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 273, Issue 2 554-R559, Copyright © 1997 by American Physiological Society

ARTICLES

L-threonine injection into PPC modifies food intake, lateral hypothalamic activity, and sympathetic discharge

M. Monda, A. Sullo, V. De Luca, M. P. Pellicano and A. Viggiano
Dipartimento di Fisiologia Umana, Seconda Universita di Napoli, Italy.

Food intake and the firing rate of lateral hypothalamic neurons and nerves innervating interscapular brown adipose tissue (IBAT), along with IBAT and colonic temperatures, were monitored in male Sprague-Dawley rats fed a threonine-free diet. These variables were measured before and after a bilateral injection of L-threonine (2 nmol into each side) into the prepiriform cortex (PPC). The same variables were also monitored in 1) rats fed a threonine-free diet and injected with saline, 2) animals fed a standard diet and injected with L-threonine, and 3) rats fed a standard diet and injected with saline. The results showed that injection of L-threonine into PPC increases food intake and firing rate of lateral hypothalamic neurons, whereas it decreases the sympathetic discharge and body temperature in animals fed a threonine-free diet. No changes were found in the animals fed a standard diet. These findings suggest a correlation between 1) threonine level in the PPC and 2) lateral hypothalamic activity and sympathetic discharge to IBAT.


This article has been cited by other articles:


Home page
 J. Nutr.Home page
D. W. Gietzen and L. J. Magrum
Molecular Mechanisms in the Brain Involved in the Anorexia of Branched-Chain Amino Acid Deficiency
J. Nutr., March 1, 2001; 131(3): 851S - 855.
[Abstract] [Full Text]

Home page
 J. Nutr.Home page
C. X. Wang, L. F. Erecius, J. L. Beverly III, and D. W. Gietzen
Essential Amino Acids Affect Interstitial Dopamine Metabolites in the Anterior Piriform Cortex of Rats
J. Nutr., September 1, 1999; 129(9): 1742 - 1745.
[Abstract] [Full Text]

Home page
 J. Nutr.Home page
D. W. Gietzen, L. F. Erecius, and Q. R. Rogers
Neurochemical Changes after Imbalanced Diets Suggest a Brain Circuit Mediating Anorectic Responses to Amino Acid Deficiency in Rats
J. Nutr., April 1, 1998; 128(4): 771 - 781.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online