AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 277: R532-R540, 1999;
0363-6119/99 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Curtis, K. S.
Right arrow Articles by Heesch, C. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Curtis, K. S.
Right arrow Articles by Heesch, C. M.
Vol. 277, Issue 2, R532-R540, August 1999

Fos expression in brain stem nuclei of pregnant rats after hydralazine-induced hypotension

Kathleen S. Curtis1,2, J. Thomas Cunningham1,2, and Cheryl M. Heesch2,3

Departments of 1 Physiology and 3 Veterinary Biomedical Sciences and 2 Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211

Fos and dopamine beta -hydroxylase immunoreactivity were evaluated in the brain stems of 21-day pregnant and virgin female rats injected with either hydralazine (HDZ; 10 mg/kg iv) or vehicle. HDZ produced significant hypotension in both groups, although baseline blood pressure was lower in pregnant rats (96 ± 2.5 mmHg) than in virgin female rats (121 ± 2.8 mmHg). There were no differences in Fos immunoreactivity in the brain stems of pregnant and virgin female rats after vehicle treatment. HDZ-induced hypotension significantly increased Fos expression in both groups; however, the magnitude of the increases differed in the caudal ventrolateral medulla (CVL), the area postrema (AP), and the rostral ventrolateral medulla (RVL). Fos expression after HDZ in pregnant rats was augmented in noncatecholaminergic neurons of the CVL but was attenuated in the AP and in noncatecholaminergic neurons in the RVL. These results are consistent with differences in the sympathetic response to hypotension between pregnant and virgin female rats and indicate that the central response to hypotension may be different in pregnant rats.

baroreflex; sympathetic activation


This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
L. Kvochina, E. M. Hasser, and C. M. Heesch
Pregnancy increases baroreflex-independent GABAergic inhibition of the RVLM in rats
Am J Physiol Regulatory Integrative Comp Physiol, December 1, 2007; 293(6): R2295 - R2305.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
E. G. Krause, K. S. Curtis, J. P. Markle, and R. J. Contreras
Oestrogen affects the cardiovascular and central responses to isoproterenol of female rats
J. Physiol., July 1, 2007; 582(1): 435 - 447.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
H. B. Gottlieb, L. L. Ji, H. Jones, M. L. Penny, T. Fleming, and J. T. Cunningham
Differential effects of water and saline intake on water deprivation-induced c-Fos staining in the rat
Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2006; 290(5): R1251 - R1261.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
V. L. Brooks, K. A. Clow, and K. P. O'Hagan
Pregnancy and acute baroreflex resetting in conscious rabbits
Am J Physiol Regulatory Integrative Comp Physiol, August 1, 2002; 283(2): R429 - R440.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
J. D. Laiprasert, R. L. Hamlin, and C. M. Heesch
Afferent baroreceptor discharge in pregnant rats
Am J Physiol Heart Circ Physiol, December 1, 2001; 281(6): H2456 - H2462.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
C. M. HEESCH and C. M. FOLEY
CNS Effects of Ovarian Hormones and Metabolites on Neural Control of Circulation
Ann. N.Y. Acad. Sci., June 1, 2001; 940(1): 348 - 360.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
G. E. Hermann, G. S. Emch, C. A. Tovar, and R. C. Rogers
c-Fos generation in the dorsal vagal complex after systemic endotoxin is not dependent on the vagus nerve
Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2001; 280(1): R289 - R299.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online