AJP - Regu Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 281: R197-R205, 2001;
0363-6119/01 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (29)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Miyazaki, T.
Right arrow Articles by Honma, K.-I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Miyazaki, T.
Right arrow Articles by Honma, K.-I.
Vol. 281, Issue 1, R197-R205, July 2001

Phase-advance shifts of human circadian pacemaker are accelerated by daytime physical exercise

Toshihiko Miyazaki, Satoko Hashimoto, Satoru Masubuchi, Sato Honma, and Ken-Ichi Honma

Department of Physiology, Hokkaido University Graduate School of Medicine, Sapporo 060 Japan

Effects of forced sleep-wake schedules with and without physical exercise were examined on the human circadian pacemaker under dim light conditions. Subjects spent 15 days in an isolation facility separately without knowing the time of day and followed a forced sleep-wake schedule of a 23 h 40-min period for 12 cycles, and physical exercise was imposed twice per waking period for 2 h each with bicycle- or rowing-type ergometers. As a result, plasma melatonin rhythm was significantly phase advanced with physical exercise, whereas it was not changed without exercise. The difference in phase was already significant 6 days after the start of exercise. The amplitude of melatonin rhythm was not affected. A single pulse of physical exercise in the afternoon or at midnight significantly phase delayed the melatonin rhythms when compared with the prepulse phase, but the amount of phase shift was not different from that observed in the sedentary controls. These findings indicate that physical exercise accelerates phase-advance shifts of the human circadian pacemaker associated with the forced sleep-wake schedule.

melatonin; rectal temperature; entrainment


This article has been cited by other articles:


Home page
 GENES CELLSHome page
Y. Yamanaka, S. Honma, and K.-i. Honma
Scheduled exposures to a novel environment with a running-wheel differentially accelerate re-entrainment of mice peripheral clocks to new light-dark cycles.
Genes Cells, May 1, 2008; 13(5): 497 - 507.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
N. Goel
An arousing, musically enhanced bird song stimulus mediates circadian rhythm phase advances in dim light
Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2006; 291(3): R822 - R827.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
M. Takimoto, A. Hamada, A. Tomoda, S. Ohdo, T. Ohmura, H. Sakato, J. Kawatani, T. Jodoi, H. Nakagawa, H. Terazono, et al.
Daily expression of clock genes in whole blood cells in healthy subjects and a patient with circadian rhythm sleep disorder
Am J Physiol Regulatory Integrative Comp Physiol, November 1, 2005; 289(5): R1273 - R1279.
[Abstract] [Full Text] [PDF]

Home page
 J Biol RhythmsHome page
R. E. Mistlberger and D. J. Skene
Nonphotic Entrainment in Humans?
J Biol Rhythms, August 1, 2005; 20(4): 339 - 352.
[Abstract] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
N. Goel
Late-night presentation of an auditory stimulus phase delays human circadian rhythms
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2005; 289(1): R209 - R216.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
L. K. Barger, K. P. Wright Jr., R. J. Hughes, and C. A. Czeisler
Daily exercise facilitates phase delays of circadian melatonin rhythm in very dim light
Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2004; 286(6): R1077 - R1084.
[Abstract] [Full Text] [PDF]

Home page
 J Biol RhythmsHome page
K.-i. Honma, S. Hashimoto, M. Nakao, and S. Honma
Period and Phase Adjustments of Human Circadian Rhythms in the Real World
J Biol Rhythms, June 1, 2003; 18(3): 261 - 270.
[Abstract] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
E. K. Baehr, C. I. Eastman, W. Revelle, S. H. L. Olson, L. F. Wolfe, and P. C. Zee
Circadian phase-shifting effects of nocturnal exercise in older compared with young adults
Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2003; 284(6): R1542 - R1550.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
O. M. Buxton, C. W. Lee, M. L'Hermite-Baleriaux, F. W. Turek, and E. Van Cauter
Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase
Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2003; 284(3): R714 - R724.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
J. Schnermann
Exercise
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2002; 283(1): R2 - R6.
[Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
K. P. Wright Jr., R. J Hughes, R. E. Kronauer, D.-J. Dijk, and C. A. Czeisler
Intrinsic near-24-h pacemaker period determines limits of circadian entrainment to a weak synchronizer in humans
PNAS, November 20, 2001; 98(24): 14027 - 14032.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
S. D. Youngstedt, D. F. Kripke, and J. A. Elliott
Circadian phase-delaying effects of bright light alone and combined with exercise in humans
Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2002; 282(1): R259 - R266.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online