AJP - Regu Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 284: R990-R999, 2003. First published January 2, 2003; doi:10.1152/ajpregu.00412.2002
0363-6119/03 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
284/4/R990    most recent
00412.2002v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (22)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Reid, S. G.
Right arrow Articles by Perry, S. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Reid, S. G.
Right arrow Articles by Perry, S. F.
Vol. 284, Issue 4, R990-R999, April 2003

Peripheral O2 chemoreceptors mediate humoral catecholamine secretion from fish chromaffin cells

Stephen G. Reid and Steve F. Perry

Department of Biology, University of Ottawa, Ottawa, Ontario, Canada K1N 6N5

This study addressed the hypothesis that the secretion of catecholamines from trout (Oncorhynchus mykiss) chromaffin cells, during hypoxia, is triggered by stimulation of O2 chemoreceptors located within the gills. Sodium cyanide was administered into the inspired water (external cyanide) or injected into the gill circulation (internal cyanide) to pharmacologically stimulate external (water sensing) or internal (blood sensing) O2 chemoreceptors, respectively. Both of these treatments caused an elevation of circulating catecholamine levels. The response to external, but not internal, cyanide was abolished by removal of the first gill arch. Hypoxia produced an increase in circulating catecholamine levels that was unaffected by removal of the first gill arch or by denervation of the pseudobranch. Cyanide and hypoxia both caused the well-documented cardiorespiratory reflexes normally observed in this species. This study demonstrates, for the first time, that gill O2 chemoreceptors can initiate the reflex that leads to catecholamine release from the chromaffin cells and that stimulation of internally oriented O2 receptors on all gill arches appears to be the physiologically important mechanism for initiating release.

epinephrine; cardiorespiratory reflexes; gills; hypoxia; Oncorhynchus mykiss


This article has been cited by other articles:


Home page
 J. Exp. Biol.Home page
E. W. Taylor, C. A. C. Leite, L. H. Florindo, T. Belao, and F. T. Rantin
The basis of vagal efferent control of heart rate in a neotropical fish, the pacu, Piaractus mesopotamicus
J. Exp. Biol., April 1, 2009; 212(7): 906 - 913.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
K. R. Olson
Hydrogen sulfide and oxygen sensing: implications in cardiorespiratory control
J. Exp. Biol., September 1, 2008; 211(17): 2727 - 2734.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
M. G. Jonz and C. A. Nurse
New developments on gill innervation: insights from a model vertebrate
J. Exp. Biol., August 1, 2008; 211(15): 2371 - 2378.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
K. R. Olson, M. J. Healy, Z. Qin, N. Skovgaard, B. Vulesevic, D. W. Duff, N. L. Whitfield, G. Yang, R. Wang, and S. F. Perry
Hydrogen sulfide as an oxygen sensor in trout gill chemoreceptors
Am J Physiol Regulatory Integrative Comp Physiol, August 1, 2008; 295(2): R669 - R680.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
R. Moudgil, E. D. Michelakis, and S. L. Archer
Hypoxic pulmonary vasoconstriction
J Appl Physiol, January 1, 2005; 98(1): 390 - 403.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
S. F. Perry, S. G. Reid, K. M. Gilmour, C. L. Boijink, J. M. Lopes, W. K. Milsom, and F. T. Rantin
A comparison of adrenergic stress responses in three tropical teleosts exposed to acute hypoxia
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2004; 287(1): R188 - R197.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online