AJP - Regu Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 288: R837-R845, 2005; doi:10.1152/ajpregu.00456.2004
0363-6119/05 $8.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (11)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Barrett, C. J.
Right arrow Articles by Malpas, S. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Barrett, C. J.
Right arrow Articles by Malpas, S. C.

CALL FOR PAPERS
Baroreflex Control of Sodium Excretion and Arterial Pressure

Problems, possibilities, and pitfalls in studying the arterial baroreflexes’ influence over long-term control of blood pressure

Carolyn J. Barrett and Simon C. Malpas

Circulatory Control Laboratory, Department of Physiology, University of Auckland, Auckland, New Zealand

While there is no disputing the critical role of baroreflexes in buffering rapid changes in arterial pressure, their role in long-term pressure control has become an area of controversy. Recent experiments using novel techniques have challenged the traditional view that arterial baroreflexes are not involved in setting chronic arterial pressure levels. Resetting of the arterial baroreflex, often used as an argument against the arterial baroreflex playing a role in long-term pressure control is rarely complete. The arterial baroreflex is just one of the many neural, hormonal, and intrinsic mechanisms involved in arterial pressure control and while the removal of the arterial baroreflex alone has little effect on mean arterial pressure it is too simplistic to suggest that the baroreflex has no role in long-term pressure control. Renal sympathetic nerve activity appears to be particularly resistant to resetting in response to ANG II-induced hypertension. Given the important role of the kidneys in long-term pressure control, we suggest there is a clear need to develop experimental techniques whereby sympathetic nerve activity to the kidneys and other organs can be monitored over periods of weeks to months.

baroreflex resetting; sinoaortic denervation; renal sympathetic nerve activity


Address for reprint requests and other correspondence: S. Malpas, Circulatory Control Laboratory, Dept. of Physiology, Univ. of Auckland Medical School, Private Bag 92019, Auckland, New Zealand (E-mail: s.malpas{at}auckland.ac.nz)




This article has been cited by other articles:


Home page
 Phil Trans R Soc AHome page
M Di Rienzo, G Parati, A Radaelli, and P Castiglioni
Baroreflex contribution to blood pressure and heart rate oscillations: time scales, time-variant characteristics and nonlinearities
Phil Trans R Soc A, April 13, 2009; 367(1892): 1301 - 1318.
[Abstract] [Full Text] [PDF]

Home page
 Exp PhysiolHome page
J. W. Osborn, V. A. Averina, and G. D. Fink
Current computational models do not reveal the importance of the nervous system in long-term control of arterial pressure
Exp Physiol, April 1, 2009; 94(4): 389 - 396.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
R. L. Khan, R. Vadigepalli, M. K. McDonald, R. F. Rogers, G. R. Gao, and J. S. Schwaber
Dynamic transcriptomic response to acute hypertension in the nucleus tractus solitarius
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2008; 295(1): R15 - R27.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
K. D. Monahan
Effect of aging on baroreflex function in humans
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2007; 293(1): R3 - R12.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
T. E. Lohmeier, T. M. Dwyer, E. D. Irwin, M. A. Rossing, and R. S. Kieval
Prolonged Activation of the Baroreflex Abolishes Obesity-Induced Hypertension
Hypertension, June 1, 2007; 49(6): 1307 - 1314.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
F. Sayk, C. Becker, C. Teckentrup, H.-L. Fehm, J. Struck, J. P. Wellhoener, and C. Dodt
To Dip or Not to Dip: On the Physiology of Blood Pressure Decrease During Nocturnal Sleep in Healthy Humans
Hypertension, May 1, 2007; 49(5): 1070 - 1076.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
Q. Fu, R. P. Shook, K. Okazaki, J. L. Hastings, S. Shibata, C. L. Conner, M. D. Palmer, and B. D. Levine
Vasomotor sympathetic neural control is maintained during sustained upright posture in humans
J. Physiol., December 1, 2006; 577(2): 679 - 687.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
A. G. Bechtold and D. A. Scheuer
Glucocorticoids act in the dorsal hindbrain to modulate baroreflex control of heart rate
Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2006; 290(4): R1003 - R1011.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
P. B. Persson
Baroreflexes in Hypertension: A Mystery Revisited
Hypertension, November 1, 2005; 46(5): 1095 - 1096.
[Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
V. L. Brooks and A. F. Sved
Pressure to change? Re-evaluating the role of baroreceptors in the long-term control of arterial pressure
Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2005; 288(4): R815 - R818.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2005 by the American Physiological Society.