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INVITED REVIEW

THE WALTER B. CANNON MEMORIAL AWARD LECTURE

Physiology in perspective: The Wisdom of the Body. Neural control of the kidney

Department of Internal Medicine and Department of Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, Iowa

Cannon equated the fluid matrix of the body with Bernard’s concept of the internal environment and emphasized the importance of "the safe-guarding of an effective fluid matrix." He further emphasized the important role of the autonomic nervous system in the establishment and maintenance of homeostasis in the internal environment. This year’s Cannon Lecture discusses the important role of the renal sympathetic nerves to regulate various aspects of overall renal function and to serve as one of the major "self-regulatory agencies which operate to preserve the constancy of the fluid matrix."

renal sympathetic nerves; renal function; homeostasis

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