AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol (February 21, 2002). doi:10.1152/ajpregu.00529.2001
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
282/6/R1746    most recent
00529.2001v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Van Vliet, B. N
Right arrow Articles by Montani, J.-P.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Van Vliet, B. N
Right arrow Articles by Montani, J.-P.

Articles in PresS, published online ahead of print February 21, 2002
Am J Physiol Regu Physiol, 10.1152/ajpregu.00529.2001
Submitted on August 31, 2001
Accepted on December 31, 1969

BAROREFLEX STABILIZATION OF THE DOUBLE (PRESSURE-RATE) PRODUCT AT 0.05 Hz IN CONSCIOUS RABBITS

Bruce N Van Vliet1*, Francesca Kiener-Belforti2, and Jean-Pierre Montani2

1 Division of Basic Medical Science, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada
2 Institute of Physiology, University of Fribourg, Fribourg, FR, Switzerland

* To whom correspondence should be addressed. E-mail: vanvliet{at}morgan.ucs.mun.ca.

The product of heart rate (HR) and systolic blood pressure (SBP), the double product (DP), is an indirect index of cardiac oxygen consumption. We used spectral analysis to test the hypothesis that baroreflex adjustments of HR stabilize the DP during spontaneous variations in SBP. SBP and HR were recorded by telemetry in 5 male conscious rabbits. HR and SBP power spectra each exhibited a low frequency peak at ~0.05 Hz that was associated with high (> 0.5) spectral coherence and a positive phase relationship between SBP and HR (SBP leading). A prominent peak was absent in the spectra of their product, suggesting that SBP and HR interacted to reduce DP variability in this frequency region. In contrast, a prominent 0.05 Hz peak was present in the power spectrum of calculated surrogates of the DP in which reflex interactions between HR and SBP had been removed. Our results suggest that baroreflex adjustments of HR stabilize the DP during spontaneous low-frequency variations in SBP in conscious rabbits.




This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
S.-J. Guild, C. J. Barrett, F. D. McBryde, B. N. Van Vliet, and S. C. Malpas
Sampling of cardiovascular data; how often and how much?
Am J Physiol Regulatory Integrative Comp Physiol, August 1, 2008; 295(2): R510 - R515.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
L. R. Leon, L. D. Walker, D. A. DuBose, and L. A. Stephenson
Biotelemetry transmitter implantation in rodents: impact on growth and circadian rhythms
Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2004; 286(5): R967 - R974.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
R. Barbieri, J. K. Triedman, and J. P. Saul
Heart rate control and mechanical cardiopulmonary coupling to assess central volume: a systems analysis
Am J Physiol Regulatory Integrative Comp Physiol, November 1, 2002; 283(5): R1210 - R1220.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 2002 by the American Physiological Society.