INVITED REVIEWS:

Mikko Nikinmaa and Bernard B. Rees

Oxygen-dependent gene expression in fishes
Am J Physiol Regul Integr Comp Physiol 288: R1079-R1090, 2005; doi:10.1152/ajpregu.00626.2004 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Harald M. Stauss

Regulator of G protein signaling (RGS2)-deficient mice: a novel model to study autonomic nervous system function
Am J Physiol Regul Integr Comp Physiol 288: R1091-R1092, 2005; doi:10.1152/ajpregu.00057.2005 [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Horng H. Chen, Alessandro Cataliotti, John A. Schirger, Fernando L. Martin, and John C. Burnett, Jr.

Equimolar doses of atrial and brain natriuretic peptides and urodilatin have differential renal actions in overt experimental heart failure
Am J Physiol Regul Integr Comp Physiol 288: R1093-R1097, 2005. First published December 30, 2004; doi:10.1152/ajpregu.00682.2004 [Abstract] [Full Text] [PDF]  

CALL FOR PAPERS:

Andrej A. Romanovsky

Editorial Focus  Vioxx, Celebrex, Bextra....Do we have a new target for anti-inflammatory and antipyretic therapy?
Am J Physiol Regul Integr Comp Physiol 288: R1098-R1099, 2005; doi:10.1152/ajpregu.00106.2005 [Full Text] [PDF]  

Sipra Saha, Linda Engström, Ludmila Mackerlova, Per-Johan Jakobsson, and Anders Blomqvist

Impaired febrile responses to immune challenge in mice deficient in microsomal prostaglandin E synthase-1
Am J Physiol Regul Integr Comp Physiol 288: R1100-R1107, 2005. First published January 27, 2005; doi:10.1152/ajpregu.00872.2004 [Abstract] [Full Text] [PDF]  

Caitlin S. Thompson, Lacy A. Holowatz, and W. Larry Kenney

Cutaneous vasoconstrictor responses to norepinephrine are attenuated in older humans
Am J Physiol Regul Integr Comp Physiol 288: R1108-R1113, 2005. First published January 20, 2005; doi:10.1152/ajpregu.00839.2004 [Abstract] [Full Text] [PDF]  

Monica Longo, Venu Jain, Yuri P. Vedernikov, Radek Bukowski, Robert E. Garfield, Gary D. Hankins, Garland D. Anderson, and George R. Saade

Fetal origins of adult vascular dysfunction in mice lacking endothelial nitric oxide synthase
Am J Physiol Regul Integr Comp Physiol 288: R1114-R1121, 2005. First published December 30, 2004; doi:10.1152/ajpregu.00367.2004 [Abstract] [Full Text] [PDF]  

M. E. Cerf, K. Williams, X. I. Nkomo, C. J. Muller, D. F. Du Toit, J. Louw, and S. A. Wolfe-Coote

Islet cell response in the neonatal rat after exposure to a high-fat diet during pregnancy
Am J Physiol Regul Integr Comp Physiol 288: R1122-R1128, 2005. First published February 10, 2005; doi:10.1152/ajpregu.00335.2004 [Abstract] [Full Text] [PDF]  

Rogerio B. Wichi, Silvia B. Souza, Dulce E. Casarini, Mariana Morris, Maria Luiza Barreto-Chaves, and Maria Claudia Irigoyen

Increased blood pressure in the offspring of diabetic mothers
Am J Physiol Regul Integr Comp Physiol 288: R1129-R1133, 2005. First published January 20, 2005; doi:10.1152/ajpregu.00366.2004 [Abstract] [Full Text] [PDF]  

APPETITE, OBESITY, DIGESTION, AND METABOLISM:

Kolapo M. Ajuwon and Michael E. Spurlock

Adiponectin inhibits LPS-induced NF-B activation and IL-6 production and increases PPAR2 expression in adipocytes
Am J Physiol Regul Integr Comp Physiol 288: R1220-R1225, 2005. First published December 16, 2004; doi:10.1152/ajpregu.00397.2004 [Abstract] [Full Text] [PDF]  

Robert R. Bowers, Thomas W. Gettys, Veronica Prpic, Ruth B. S. Harris, and Timothy J. Bartness

Short photoperiod exposure increases adipocyte sensitivity to noradrenergic stimulation in Siberian hamsters
Am J Physiol Regul Integr Comp Physiol 288: R1354-R1360, 2005; doi:10.1152/ajpregu.00792.2004 [Abstract] [Full Text] [PDF]  

Christy L. White, H. Doug Braymer, David A. York, and George A. Bray

Effect of a high or low ambient perinatal temperature on adult obesity in Osborne-Mendel and S5B/Pl rats
Am J Physiol Regul Integr Comp Physiol 288: R1376-R1384, 2005. First published January 27, 2005; doi:10.1152/ajpregu.00162.2004 [Abstract] [Full Text] [PDF]  

Jens Jordan, Georg Brabant, Marina Brinsuk, Jens Tank, Rüdiger Horn, Friedrich C. Luft, and Andreas Busjahn

Heritability of free and receptor-bound leptin in normal twins
Am J Physiol Regul Integr Comp Physiol 288: R1411-R1416, 2005. First published December 16, 2004; doi:10.1152/ajpregu.00446.2004 [Abstract] [Full Text] [PDF]  

GENETICALLY MODIFIED ANIMALS AND MODEL ORGANISMS:

Volkmar Gross, Jens Tank, Michael Obst, Ralph Plehm, Kendall J. Blumer, Andrè Diedrich, Jens Jordan, and Friedrich C. Luft

Autonomic nervous system and blood pressure regulation in RGS2-deficient mice
Am J Physiol Regul Integr Comp Physiol 288: R1134-R1142, 2005. First published January 20, 2005; doi:10.1152/ajpregu.00246.2004 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND CYTOKINES:

Weerapan Khovidhunkit, Jean Pierre Hachem, Katalin F. Medzihradszky, Philippe N. Duchateau, Judy K. Shigenaga, Arthur H. Moser, Irina Movsesyan, Josefina Naya-Vigne, John P. Kane, Kenneth R. Feingold, and Carl Grunfeld

Parotid secretory protein is an HDL-associated protein with anticandidal activity
Am J Physiol Regul Integr Comp Physiol 288: R1306-R1315, 2005. First published January 6, 2005; doi:10.1152/ajpregu.00007.2004 [Abstract] [Full Text] [PDF]  

Hua Tian Gan and J. D. Z. Chen

Roles of nitric oxide and prostaglandins in pathogenesis of delayed colonic transit after burn injury in rats
Am J Physiol Regul Integr Comp Physiol 288: R1316-R1324, 2005. First published January 13, 2005; doi:10.1152/ajpregu.00733.2004 [Abstract] [Full Text] [PDF]  

RENAL HEMODYNAMICS AND CARDIORENAL INTEGRATION:

Donald J. Marsh, Olga V. Sosnovtseva, Ki H. Chon, and Niels-Henrik Holstein-Rathlou

Nonlinear interactions in renal blood flow regulation
Am J Physiol Regul Integr Comp Physiol 288: R1143-R1159, 2005. First published January 27, 2005; doi:10.1152/ajpregu.00539.2004 [Abstract] [Full Text] [PDF]  

Donald J. Marsh, Olga V. Sosnovtseva, Alexey N. Pavlov, Kay-Pong Yip, and Niels-Henrik Holstein-Rathlou

Frequency encoding in renal blood flow regulation
Am J Physiol Regul Integr Comp Physiol 288: R1160-R1167, 2005. First published January 20, 2005; doi:10.1152/ajpregu.00540.2004 [Abstract] [Full Text] [PDF]  

NEUROHUMORAL CONTROL OF CARDIOVASCULAR FUNCTION:

Armin Just, Andrea J. M. Olson, John R. Falck, and William J. Arendshorst

NO and NO-independent mechanisms mediate ET_B receptor buffering of ET-1-induced renal vasoconstriction in the rat
Am J Physiol Regul Integr Comp Physiol 288: R1168-R1177, 2005. First published December 23, 2004; doi:10.1152/ajpregu.00550.2004 [Abstract] [Full Text] [PDF]  

Meghan M. Taylor, Jennifer R. Baker, and Willis K. Samson

Brain-derived adrenomedullin controls blood volume through the regulation of arginine vasopressin production and release
Am J Physiol Regul Integr Comp Physiol 288: R1203-R1210, 2005. First published January 6, 2005; doi:10.1152/ajpregu.00781.2004 [Abstract] [Full Text] [PDF]  

Cécile Héliès-Toussaint, Christophe Moinard, Carole Rasmusen, Imène Tabbi-Anneni, Luc Cynober, and Alain Grynberg

Aortic banding in rat as a model to investigate malnutrition associated with heart failure
Am J Physiol Regul Integr Comp Physiol 288: R1325-R1331, 2005. First published January 6, 2005; doi:10.1152/ajpregu.00320.2004 [Abstract] [Full Text] [PDF]  

Brian E. Hunt and William B. Farquhar

Nonlinearities and asymmetries of the human cardiovagal baroreflex
Am J Physiol Regul Integr Comp Physiol 288: R1339-R1346, 2005. First published March 3, 2005; doi:10.1152/ajpregu.00038.2004 [Abstract] [Full Text] [PDF]  

DEVELOPMENTAL PHYSIOLOGY AND PREGNANCY:

Dean A. Myers, Paige A. Bell, Kimberly Hyatt, Malgorzata Mlynarczyk, and Charles A. Ducsay

Long-term hypoxia enhances proopiomelanocortin processing in the near-term ovine fetus
Am J Physiol Regul Integr Comp Physiol 288: R1178-R1184, 2005. First published December 23, 2004; doi:10.1152/ajpregu.00697.2004 [Abstract] [Full Text] [PDF]  

Jeffrey M. Purkerson and George J. Schwartz

Expression of membrane-associated carbonic anhydrase isoforms IV, IX, XII, and XIV in the rabbit: induction of CA IV and IX during maturation
Am J Physiol Regul Integr Comp Physiol 288: R1256-R1263, 2005; doi:10.1152/ajpregu.00735.2004 [Abstract] [Full Text] [PDF]  

Kai Chen, Luke C. Carey, Jingfang Liu, Nancy K. Valego, Stephen B. Tatter, and James C. Rose

The effect of hypothalamo-pituitary disconnection on the renin-angiotensin system in the late-gestation fetal sheep
Am J Physiol Regul Integr Comp Physiol 288: R1279-R1287, 2005. First published December 16, 2004; doi:10.1152/ajpregu.00560.2004 [Abstract] [Full Text] [PDF]  

Sean W. Limesand, Jan Jensen, John C. Hutton, and William W. Hay, Jr.

Diminished -cell replication contributes to reduced -cell mass in fetal sheep with intrauterine growth restriction
Am J Physiol Regul Integr Comp Physiol 288: R1297-R1305, 2005. First published January 13, 2005; doi:10.1152/ajpregu.00494.2004 [Abstract] [Full Text] [PDF]  

ENVIRONMENTAL, EXERCISE AND RESPIRATORY PHYSIOLOGY:

Brian J. Koos, Yoshikazu Kawasaki, Young-Han Kim, and Fanor Bohorquez

Adenosine A_2A-receptor blockade abolishes the roll-off respiratory response to hypoxia in awake lambs
Am J Physiol Regul Integr Comp Physiol 288: R1185-R1194, 2005. First published December 23, 2004; doi:10.1152/ajpregu.00723.2004 [Abstract] [Full Text] [PDF]  

Xinnian Chen, Ki H. Chon, and Irene C. Solomon

Chemical activation of pre-Bötzinger complex in vivo reduces respiratory network complexity
Am J Physiol Regul Integr Comp Physiol 288: R1237-R1247, 2005. First published January 13, 2005; doi:10.1152/ajpregu.00650.2004 [Abstract] [Full Text] [PDF]  

Takao Sugiura, Noritaka Abe, Mai Nagano, Katsumasa Goto, Kunihiro Sakuma, Hisashi Naito, Toshitada Yoshioka, and Scott K. Powers

Changes in PKB/Akt and calcineurin signaling during recovery in atrophied soleus muscle induced by unloading
Am J Physiol Regul Integr Comp Physiol 288: R1273-R1278, 2005; doi:10.1152/ajpregu.00688.2004 [Abstract] [Full Text] [PDF]  

Christiaan Leeuwenburgh, Cathy M. Gurley, Beau A. Strotman, and Esther E. Dupont-Versteegden

Age-related differences in apoptosis with disuse atrophy in soleus muscle
Am J Physiol Regul Integr Comp Physiol 288: R1288-R1296, 2005. First published January 13, 2005; doi:10.1152/ajpregu.00576.2004 [Abstract] [Full Text] [PDF]  

Tomoko Kuwahara, Yoshimitsu Inoue, Miyako Abe, Yuki Sato, and Narihiko Kondo

Effects of menstrual cycle and physical training on heat loss responses during dynamic exercise at moderate intensity in a temperate environment
Am J Physiol Regul Integr Comp Physiol 288: R1347-R1353, 2005. First published January 27, 2005; doi:10.1152/ajpregu.00547.2004 [Abstract] [Full Text] [PDF]  

Dennis Jensen, Larry A. Wolfe, Lubomira Slatkovska, Katherine A. Webb, Gregory A. L. Davies, and Denis E. O'Donnell

Effects of human pregnancy on the ventilatory chemoreflex response to carbon dioxide
Am J Physiol Regul Integr Comp Physiol 288: R1369-R1375, 2005. First published January 27, 2005; doi:10.1152/ajpregu.00862.2004 [Abstract] [Full Text] [PDF]  

Shaun W. Phillips, Gerard L. Gebber, and Susan M. Barman

Medullary lateral tegmental field: control of respiratory rate and vagal lung inflation afferent influences on sympathetic nerve discharge
Am J Physiol Regul Integr Comp Physiol 288: R1396-R1410, 2005. First published December 16, 2004; doi:10.1152/ajpregu.00632.2004 [Abstract] [Full Text] [PDF]  

COMPARATIVE AND EVOLUTIONARY PHYSIOLOGY:

Sean P. Place and Gretchen E. Hofmann

Comparison of Hsc70 orthologs from polar and temperate notothenioid fishes: differences in prevention of aggregation and refolding of denatured proteins
Am J Physiol Regul Integr Comp Physiol 288: R1195-R1202, 2005. First published January 6, 2005; doi:10.1152/ajpregu.00660.2004 [Abstract] [Full Text] [PDF]  

Mauricio Avigdor, Shannon D. Sullivan, and Paul D. Heideman

Response to selection for photoperiod responsiveness on the density and location of mature GnRH-releasing neurons
Am J Physiol Regul Integr Comp Physiol 288: R1226-R1236, 2005. First published January 13, 2005; doi:10.1152/ajpregu.00562.2004 [Abstract] [Full Text] [PDF]  

Samantha J. Richardson, Julie A. Monk, Caroline A. Shepherdley, Lars O. E. Ebbesson, Frank Sin, Deborah M. Power, Peter B. Frappell, Josef Köhrle, and Marilyn B. Renfree

Developmentally regulated thyroid hormone distributor proteins in marsupials, a reptile, and fish
Am J Physiol Regul Integr Comp Physiol 288: R1264-R1272, 2005. First published January 13, 2005; doi:10.1152/ajpregu.00793.2004 [Abstract] [Full Text] [PDF]  

Brian S. Shepherd, Katherine Drennon, Jaime Johnson, Joel W. Nichols, Richard C. Playle, Thomas D. Singer, and Mathilakath M. Vijayan

Salinity acclimation affects the somatotropic axis in rainbow trout
Am J Physiol Regul Integr Comp Physiol 288: R1385-R1395, 2005. First published December 16, 2004; doi:10.1152/ajpregu.00443.2004 [Abstract] [Full Text] [PDF]  

WATER AND ELECTROLYTE HOMEOSTASIS:

Steven L. Bealer

Increased dietary sodium inhibits baroreflex-induced bradycardia during acute sodium loading
Am J Physiol Regul Integr Comp Physiol 288: R1211-R1219, 2005. First published January 6, 2005; doi:10.1152/ajpregu.00244.2004 [Abstract] [Full Text] [PDF]  

Virginia L. Brooks, Yue Qi, and Theresa L. O'Donaughy

Increased osmolality of conscious water-deprived rats supports arterial pressure and sympathetic activity via a brain action
Am J Physiol Regul Integr Comp Physiol 288: R1248-R1255, 2005. First published January 20, 2005; doi:10.1152/ajpregu.00638.2004 [Abstract] [Full Text] [PDF]  

Larissa V. Rodríguez, Shinhong Chen, Gregory S. Jack, Fernando de Almeida, Kyo Won Lee, and Rong Zhang

New objective measures to quantify stress urinary incontinence in a novel durable animal model of intrinsic sphincter deficiency
Am J Physiol Regul Integr Comp Physiol 288: R1332-R1338, 2005. First published January 13, 2005; doi:10.1152/ajpregu.00760.2004 [Abstract] [Full Text] [PDF]  

Shachar Eylam and Alan C. Spector

Taste discrimination between NaCl and KCl is disrupted by amiloride in inbred mice with amiloride-insensitive chorda tympani nerves
Am J Physiol Regul Integr Comp Physiol 288: R1361-R1368, 2005; doi:10.1152/ajpregu.00796.2004 [Abstract] [Full Text] [PDF]  

Jaap Mulder, Sumana Chakravarty, Maha N. Haddad, Michel Baum, and Raymond Quigley

Glucocorticoids increase osmotic water permeability (P_f) of neonatal rabbit renal brush border membrane vesicles
Am J Physiol Regul Integr Comp Physiol 288: R1417-R1421, 2005. First published January 20, 2005; doi:10.1152/ajpregu.00448.2004 [Abstract] [Full Text] [PDF]  

CORRIGENDA:

Corrigendum
Am J Physiol Regul Integr Comp Physiol 288: R1422-R1422, 2005; doi:10.1152/ajpregu.00151.2005 [Full Text] [PDF]  

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