INVITED REVIEWS:

Thomas H. Adair

Growth regulation of the vascular system: an emerging role for adenosine
Am J Physiol Regul Integr Comp Physiol 289: R283-R296, 2005; doi:10.1152/ajpregu.00840.2004 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Paul Trayhurn

White adipose tissue grafts—keeping in contact
Am J Physiol Regul Integr Comp Physiol 289: R297-R298, 2005; doi:10.1152/ajpregu.00284.2005 [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Chao-Hung Wang, Shu-Hong Li, Richard D. Weisel, Paul W. M. Fedak, Agnes Hung, Ren-Ke Li, Vivek Rao, Keith Hyland, Wen-Jin Cherng, Lee Errett, Yves Leclerc, Daniel Bonneau, David A. Latter, and Subodh Verma

Tetrahydrobiopterin deficiency exaggerates intimal hyperplasia after vascular injury
Am J Physiol Regul Integr Comp Physiol 289: R299-R304, 2005. First published March 17, 2005; doi:10.1152/ajpregu.00269.2004 [Abstract] [Full Text] [PDF]  

CALL FOR PAPERS:

Kieren Mather and Subodh Verma

Editorial Focus  Function determines structure in the vasculature: lessons from insulin resistance
Am J Physiol Regul Integr Comp Physiol 289: R305-R306, 2005; doi:10.1152/ajpregu.00297.2005 [Full Text] [PDF]  

Jefferson C. Frisbee

Reduced nitric oxide bioavailability contributes to skeletal muscle microvessel rarefaction in the metabolic syndrome
Am J Physiol Regul Integr Comp Physiol 289: R307-R316, 2005. First published March 31, 2005; doi:10.1152/ajpregu.00114.2005 [Abstract] [Full Text] [PDF]  

Robin M. McAllen and Michael J. McKinley

Editorial Focus  Personal body maps
Am J Physiol Regul Integr Comp Physiol 289: R317-R318, 2005; doi:10.1152/ajpregu.00323.2005 [Full Text] [PDF]  

Le H. Hua, Irina A. Strigo, Leslie C. Baxter, Sterling C. Johnson, and A. D. (Bud) Craig

Anteroposterior somatotopy of innocuous cooling activation focus in human dorsal posterior insular cortex
Am J Physiol Regul Integr Comp Physiol 289: R319-R325, 2005. First published March 31, 2005; doi:10.1152/ajpregu.00123.2005 [Abstract] [Full Text] [PDF]  

Petter H. Kvadsheim, Lars P. Folkow, and Arnoldus Schytte Blix

Inhibition of shivering in hypothermic seals during diving
Am J Physiol Regul Integr Comp Physiol 289: R326-R331, 2005. First published March 10, 2005; doi:10.1152/ajpregu.00708.2004 [Abstract] [Full Text] [PDF]  

Vit Perlik, Zhongua Li, Sarita Goorha, Leslie R. Ballou, and Clark M. Blatteis

LPS-activated complement, not LPS per se, triggers the early release of PGE₂ by Kupffer cells
Am J Physiol Regul Integr Comp Physiol 289: R332-R339, 2005. First published March 31, 2005; doi:10.1152/ajpregu.00567.2004 [Abstract] [Full Text] [PDF]  

Christoph Rummel, Stephan W. Barth, Thilo Voss, Stefan Korte, Rüdiger Gerstberger, Thomas Hübschle, and Joachim Roth

Localized vs. systemic inflammation in guinea pigs: a role for prostaglandins at distinct points of the fever induction pathways?
Am J Physiol Regul Integr Comp Physiol 289: R340-R347, 2005. First published April 14, 2005; doi:10.1152/ajpregu.00104.2005 [Abstract] [Full Text] [PDF]  

Alexandre A. Steiner, Sumana Chakravarty, Jared R. Robbins, Alexander S. Dragic, Jennifer Pan, Miles Herkenham, and Andrej A. Romanovsky

Thermoregulatory responses of rats to conventional preparations of lipopolysaccharide are caused by lipopolysaccharide per se— not by lipoprotein contaminants
Am J Physiol Regul Integr Comp Physiol 289: R348-R352, 2005. First published April 28, 2005; doi:10.1152/ajpregu.00223.2005 [Abstract] [Full Text] [PDF]  

Paul J. Currie, Aaisha Mirza, Rebecca Fuld, Diana Park, and Joseph R. Vasselli

Ghrelin is an orexigenic and metabolic signaling peptide in the arcuate and paraventricular nuclei
Am J Physiol Regul Integr Comp Physiol 289: R353-R358, 2005. First published April 7, 2005; doi:10.1152/ajpregu.00756.2004 [Abstract] [Full Text] [PDF]  

Catherine M. Kotz, Mary A. Mullett, and ChuanFeng Wang

Diminished feeding responsiveness to orexin A (hypocretin 1) in aged rats is accompanied by decreased neuronal activation
Am J Physiol Regul Integr Comp Physiol 289: R359-R366, 2005. First published May 5, 2005; doi:10.1152/ajpregu.00717.2004 [Abstract] [Full Text] [PDF]  

A. J. Thorpe, J. A. Teske, and C. M. Kotz

Orexin A-induced feeding is augmented by caloric challenge
Am J Physiol Regul Integr Comp Physiol 289: R367-R372, 2005. First published June 9, 2005; doi:10.1152/ajpregu.00737.2004 [Abstract] [Full Text] [PDF]  

Kimberly A. Singh, Carol N. Boozer, and Joseph R. Vasselli

Acute insulin-induced elevations of circulating leptin and feeding inhibition in lean but not obese rats
Am J Physiol Regul Integr Comp Physiol 289: R373-R379, 2005. First published March 17, 2005; doi:10.1152/ajpregu.00738.2004 [Abstract] [Full Text] [PDF]  

APPETITE, OBESITY, DIGESTION, AND METABOLISM:

Eva L. Lacy and Timothy J. Bartness

Effects of white adipose tissue grafts on total body fat and cellularity are dependent on graft type and location
Am J Physiol Regul Integr Comp Physiol 289: R380-R388, 2005. First published March 31, 2005; doi:10.1152/ajpregu.00116.2005 [Abstract] [Full Text] [PDF]  

S. Eisen, R. J. Phillips, N. Geary, E. A. Baronowsky, T. L. Powley, and G. P. Smith

Inhibitory effects on intake of cholecystokinin-8 and cholecystokinin-33 in rats with hepatic proper or common hepatic branch vagal innervation
Am J Physiol Regul Integr Comp Physiol 289: R456-R462, 2005. First published April 14, 2005; doi:10.1152/ajpregu.00062.2005 [Abstract] [Full Text] [PDF]  

Ellen E. Ladenheim, M. Emond, and T. H. Moran

Leptin enhances feeding suppression and neural activation produced by systemically administered bombesin
Am J Physiol Regul Integr Comp Physiol 289: R473-R477, 2005. First published April 28, 2005; doi:10.1152/ajpregu.00835.2004 [Abstract] [Full Text] [PDF]  

Andrea S. Rossi, Yolanda B. Lombardo, Jean-Marc Lacorte, Adriana G. Chicco, Christine Rouault, Gérard Slama, and Salwa W. Rizkalla

Dietary fish oil positively regulates plasma leptin and adiponectin levels in sucrose-fed, insulin-resistant rats
Am J Physiol Regul Integr Comp Physiol 289: R486-R494, 2005; doi:10.1152/ajpregu.00846.2004 [Abstract] [Full Text] [PDF]  

Haifei Shi and Timothy J. Bartness

White adipose tissue sensory nerve denervation mimics lipectomy-induced compensatory increases in adiposity
Am J Physiol Regul Integr Comp Physiol 289: R514-R520, 2005. First published April 28, 2005; doi:10.1152/ajpregu.00036.2005 [Abstract] [Full Text] [PDF]  

Terry L. Powley, Michael M. Chi, Elizabeth A. Baronowsky, and Robert J. Phillips

Gastrointestinal tract innervation of the mouse: afferent regeneration and meal patterning after vagotomy
Am J Physiol Regul Integr Comp Physiol 289: R563-R574, 2005. First published April 14, 2005; doi:10.1152/ajpregu.00167.2005 [Abstract] [Full Text] [PDF]  

INFLAMMATION AND CYTOKINES:

Courtney C. Fleck and Hannah V. Carey

Modulation of apoptotic pathways in intestinal mucosa during hibernation
Am J Physiol Regul Integr Comp Physiol 289: R586-R595, 2005. First published April 14, 2005; doi:10.1152/ajpregu.00100.2005 [Abstract] [Full Text] [PDF]  

NEUROHUMORAL CONTROL OF CARDIOVASCULAR FUNCTION:

Hanne M. Schiøtz Thorud, Annicke Stranda, Jon-Arne Birkeland, Per K. Lunde, Ivar Sjaastad, Svein O. Kolset, Ole M. Sejersted, and Per O. Iversen

Enhanced matrix metalloproteinase activity in skeletal muscles of rats with congestive heart failure
Am J Physiol Regul Integr Comp Physiol 289: R389-R394, 2005. First published March 31, 2005; doi:10.1152/ajpregu.00067.2005 [Abstract] [Full Text] [PDF]  

Gerald M. Herrera, Bud Etherton, Bernhard Nausch, and Mark T. Nelson

Negative feedback regulation of nerve-mediated contractions by K_Ca channels in mouse urinary bladder smooth muscle
Am J Physiol Regul Integr Comp Physiol 289: R402-R409, 2005. First published April 21, 2005; doi:10.1152/ajpregu.00488.2004 [Abstract] [Full Text] [PDF]  

Weike Tao, Victor T. Enoh, Cheng Y. Lin, William E. Johnston, Peng Li, and Edward R. Sherwood

Cardiovascular dysfunction caused by cecal ligation and puncture is attenuated in CD8 knockout mice treated with anti-asialoGM1
Am J Physiol Regul Integr Comp Physiol 289: R478-R485, 2005. First published April 21, 2005; doi:10.1152/ajpregu.00081.2005 [Abstract] [Full Text] [PDF]  

Eugene Nalivaiko, Youichirou Ootsuka, and William W. Blessing

Activation of 5-HT_1A receptors in the medullary raphe reduces cardiovascular changes elicited by acute psychological and inflammatory stresses in rabbits
Am J Physiol Regul Integr Comp Physiol 289: R596-R604, 2005. First published March 31, 2005; doi:10.1152/ajpregu.00845.2004 [Abstract] [Full Text] [PDF]  

DEVELOPMENTAL PHYSIOLOGY AND PREGNANCY:

Nancy K. Valego, Yixin Su, Luke C. Carey, Sharla F. Young, Stephen B. Tatter, Jinjuan Wang, and James C. Rose

Hypothalamic-pituitary disconnection in fetal sheep blocks the peripartum increases in adrenal responsiveness and adrenal ACTH receptor expression
Am J Physiol Regul Integr Comp Physiol 289: R410-R417, 2005. First published March 31, 2005; doi:10.1152/ajpregu.00025.2005 [Abstract] [Full Text] [PDF]  

Charles E. Wood, Gin-Fu Chen, and Maureen Keller-Wood

Expression of nitric oxide synthase isoforms is reduced in late-gestation ovine fetal brainstem
Am J Physiol Regul Integr Comp Physiol 289: R613-R619, 2005; doi:10.1152/ajpregu.00722.2004 [Abstract] [Full Text] [PDF]  

ENVIRONMENTAL, EXERCISE AND RESPIRATORY PHYSIOLOGY:

Adam J. Chicco, Carole M. Schneider, and Reid Hayward

Voluntary exercise protects against acute doxorubicin cardiotoxicity in the isolated perfused rat heart
Am J Physiol Regul Integr Comp Physiol 289: R424-R431, 2005. First published April 21, 2005; doi:10.1152/ajpregu.00636.2004 [Abstract] [Full Text] [PDF]  

Tomoyuki Ito, Toshiyuki Itoh, Takashi Hayano, Katsuya Yamauchi, and Akira Takamata

Plasma hyperosmolality augments peripheral vascular response to baroreceptor unloading during heat stress
Am J Physiol Regul Integr Comp Physiol 289: R432-R440, 2005. First published April 21, 2005; doi:10.1152/ajpregu.00027.2004 [Abstract] [Full Text] [PDF]  

S. D. Sandiford, H. J. Green, T. A. Duhamel, J. D. Schertzer, J. D. Perco, and J. Ouyang

Muscle Na-K-pump and fatigue responses to progressive exercise in normoxia and hypoxia
Am J Physiol Regul Integr Comp Physiol 289: R441-R449, 2005. First published April 28, 2005; doi:10.1152/ajpregu.00652.2004 [Abstract] [Full Text] [PDF]  

Michael B. Harris and Walter M. St.-John

Phasic pulmonary stretch receptor feedback modulates both eupnea and gasping in an in situ rat preparation
Am J Physiol Regul Integr Comp Physiol 289: R450-R455, 2005. First published April 14, 2005; doi:10.1152/ajpregu.00750.2004 [Abstract] [Full Text] [PDF]  

Coral L. Murrant

Stimulation characteristics that determine arteriolar dilation in skeletal muscle
Am J Physiol Regul Integr Comp Physiol 289: R505-R513, 2005; doi:10.1152/ajpregu.00571.2004 [Abstract] [Full Text] [PDF]  

Trevor A. Day and Richard J. A. Wilson

Specific carotid body chemostimulation is sufficient to elicit phrenic poststimulus frequency decline in a novel in situ dual-perfused rat preparation
Am J Physiol Regul Integr Comp Physiol 289: R532-R544, 2005. First published March 31, 2005; doi:10.1152/ajpregu.00812.2004 [Abstract] [Full Text] [PDF]  

COMPARATIVE AND EVOLUTIONARY PHYSIOLOGY:

Patricia L. Seymour, Samantha L. Dettloff, Juli E. Jones, and George N. Wade

Corticotropin-releasing factor receptor subtypes mediating nutritional suppression of estrous behavior in Syrian hamsters
Am J Physiol Regul Integr Comp Physiol 289: R418-R423, 2005. First published April 14, 2005; doi:10.1152/ajpregu.00168.2005 [Abstract] [Full Text] [PDF]  

John A. Hammond, Kimberley A. Bennett, Michael J. Walton, and Ailsa J. Hall

Molecular cloning and expression of leptin in gray and harbor seal blubber, bone marrow, and lung and its potential role in marine mammal respiratory physiology
Am J Physiol Regul Integr Comp Physiol 289: R545-R553, 2005. First published April 14, 2005; doi:10.1152/ajpregu.00203.2004 [Abstract] [Full Text] [PDF]  

P. G. Osborne, J. Sato, N. Shuke, and M. Hashimoto

Sympathetic -adrenergic regulation of blood flow and volume in hamsters arousing from hibernation
Am J Physiol Regul Integr Comp Physiol 289: R554-R562, 2005. First published April 21, 2005; doi:10.1152/ajpregu.00004.2005 [Abstract] [Full Text] [PDF]  

Tsutomu Nakada, Kambiz Zandi-Nejad, Yukihiro Kurita, Hisayuki Kudo, Vadjista Broumand, Charles Y. Kwon, Adriana Mercado, David B. Mount, and Shigehisa Hirose

Roles of Slc13a1 and Slc26a1 sulfate transporters of eel kidney in sulfate homeostasis and osmoregulation in freshwater
Am J Physiol Regul Integr Comp Physiol 289: R575-R585, 2005. First published March 31, 2005; doi:10.1152/ajpregu.00725.2004 [Abstract] [Full Text] [PDF]  

G. S. Stewart, C. Graham, S. Cattell, T. P. L. Smith, N. L. Simmons, and C. P. Smith

UT-B is expressed in bovine rumen: potential role in ruminal urea transport
Am J Physiol Regul Integr Comp Physiol 289: R605-R612, 2005. First published April 21, 2005; doi:10.1152/ajpregu.00127.2005 [Abstract] [Full Text] [PDF]  

SLEEP AND TEMPERATURE REGULATION:

Ana C. Ribeiro and Levente Kapás

Day- and nighttime injection of a nitric oxide synthase inhibitor elicits opposite sleep responses in rats
Am J Physiol Regul Integr Comp Physiol 289: R521-R531, 2005. First published April 28, 2005; doi:10.1152/ajpregu.00605.2004 [Abstract] [Full Text] [PDF]  

WATER AND ELECTROLYTE HOMEOSTASIS:

Volker Vallon, Dan Yang Huang, Florian Grahammer, Amanda W. Wyatt, Hartmut Osswald, Peer Wulff, Dietmar Kuhl, and Florian Lang

SGK1 as a determinant of kidney function and salt intake in response to mineralocorticoid excess
Am J Physiol Regul Integr Comp Physiol 289: R395-R401, 2005; doi:10.1152/ajpregu.00731.2004 [Abstract] [Full Text] [PDF]  

Joseph T. Rogers, Monika Patel, Kathleen M. Gilmour, and Chris M. Wood

Mechanisms behind Pb-induced disruption of Na⁺ and Cl^– balance in rainbow trout (Oncorhynchus mykiss)
Am J Physiol Regul Integr Comp Physiol 289: R463-R472, 2005; doi:10.1152/ajpregu.00362.2004 [Abstract] [Full Text] [PDF]  

Mark R. Rheault, Donna M. Debicki, and Michael J. O'Donnell

Characterization of tetraethylammonium uptake across the basolateral membrane of the Drosophila Malpighian (renal) tubule
Am J Physiol Regul Integr Comp Physiol 289: R495-R504, 2005. First published April 28, 2005; doi:10.1152/ajpregu.00109.2005 [Abstract] [Full Text] [PDF]  

Kay-Pong Yip

Innovative Methodology  Flash photolysis of caged nitric oxide inhibits proximal tubular fluid reabsorption in free-flow nephron
Am J Physiol Regul Integr Comp Physiol 289: R620-R626, 2005. First published March 24, 2005; doi:10.1152/ajpregu.00610.2004 [Abstract] [Full Text] [PDF]  

POINT-COUNTERPOINT:

J. Gisolf, A. Gisolf, J. J. van Lieshout, and J. M. Karemaker

The siphon controversy: an integration of concepts and the brain as baffle
Am J Physiol Regul Integr Comp Physiol 289: R627-R629, 2005; doi:10.1152/ajpregu.00709.2004 [Full Text] [PDF]  

James W. Hicks and James R. Munis

The siphon controversy counterpoint: the brain need not be "baffling"
Am J Physiol Regul Integr Comp Physiol 289: R629-R632, 2005; doi:10.1152/ajpregu.00810.2004 [Full Text] [PDF]  

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