Table 3.

Effects of food deprivation on water intake and refeeding food intake in DMNL and Sham rats

Post (n = 7) Lat (n = 8) Vent (n = 7) Dor (n = 7) Trial 1 Sham (n = 13) Ant (n = 7) Trial 2 Sham (n = 9)
24-h WI
 Before FD, ml28.3 ± 1.4 29.6 ± 1.2 32.5 ± 2.334.7 ± 4.1 35.0 ± 1.8 30.9 ± 0.931.2 ± 1.0
 During FD, ml 19.5 ± 2.524.4 ± 2.7 35.1 ± 5.9 27.3 ± 3.327.7 ± 2.0 16.1 ± 2.7 18.6 ± 1.9
P <0.05 NS NS NSNS <0.01 <0.01
 During FD, %69.7 ± 9.1 82.7 ± 8.6 110.3 ± 20.784.4 ± 13.8 80.3 ± 6.0 51.7 ± 8.359.0 ± 5.9
1-h FI post-FD, % 24.4 ± 3.227.9 ± 2.6 31.9 ± 5.3 22.7 ± 5.029.1 ± 2.7 27.2 ± 0.93-152 23.6 ± 1.1
24 h FI
 Before FD, g 21.7 ± 0.73-151 23.0 ± 0.8 21.5 ± 0.63-151 23.1 ± 0.423.5 ± 0.5 24.7 ± 0.5 25.6 ± 0.4
 Post-FD, g 26.6 ± 0.93-150 28.7 ± 1.026.3 ± 0.73-150 27.3 ± 1.1 29.1 ± 0.628.9 ± 0.7 30.1 ± 0.7
P <0.01 <0.01<0.01 <0.01 <0.01 <0.01 <0.01
 Post-FD, % 122.9 ± 1.8 124.7 ± 3.5122.5 ± 1.7 117.9 ± 3.7 124.4 ± 2.6119.1 ± 1.3 117.5 ± 1.1
  • All values except P values are means ± SE; n = no. of rats. A second trial was conducted with an Ant group and a Sham group (see materials and methods). All statistical comparisons for Ant group are made with trial 2 Sham group; all other statistical comparisons are made with trial 1 Sham group. Water intake (WI) during food deprivation (FD) is expressed as percentage of 24-h baseline WI. One-hour refeeding food intake (FI) post-FD and 24-h FI post-FD are expressed as percentage of 24-h baseline FI.

  • F3-150 P < 0.05 vs. trial 1 Sham group;

  • F3-151 P < 0.052 vs. trial 1 Sham group;

  • F3-152 P < 0.05 vs. trial 2 Sham group. NS, not significant.