Table 1.

Frequency of spontaneous contractions in uterine muscle strips after intracolonic instillation of saline or TNBS

Contraction Frequency, min−1
SalineMDS < 5MDS > 5
LM1.00±0.08 (n=14)0.95±0.09ns (n=11)0.61±0.03 (n=10)
CM1.47±0.11* (n=16)1.00±0.18 (n=10)ND (n=10)
  • Values are means ± SE from 3–4 replicates per rat; n = no. of rats. MDS, macroscopic damage score in the colon; LM, longitudinal muscle; CM, circular muscle; ND, not determinable; TNBS, trinitrobenzenesulfonic acid.

  • * P < 0.01 vs. longitudinal muscle;

  • P < 0.05 and

  • P < 0.001 compared with respective saline control. ns, not significant.