Table 1.

Baseline characteristics of animals used in the present study

Lean Zucker RatsObese Zucker Rats
ControlTempoll-NAMEl-NAME/HydralazineControlTempolTempol/l-NAME
(n = 8)(n = 5)(n = 5)(n = 5)(n = 8)(n = 5)(n = 5)
Mass, g351±14332±18357±15350±15662±17*660±17*651±18*
MAP, mmHg101±5102±5126±5*96±8125±5*119±5*137±5*
[Glucose]blood, mg/dl96±1296±1399±14111±16204±16*212±16*218±19*
[Insulin]plasma, ng/ml1.8±0.51.5±0.41.3±0.51.6±0.416.2±2.4*16.1±1.7*16.8±2.4*
[Cholesterol]plasma, mg/dl59±778±1075±1081±988±9*140±14*101±19*
[Triglycerides]plasma, mg/dl69±1089±1898±15102±15368±20*368±27*377±35*
[8-isoprostane]plasma, ng/ml64±648±770±858±7139±9*88±1281±9
  • Values are presented as means ± SE.

  • * P < 0.05 vs. lean Zucker rats (LZR; control);

  • P < 0.05 vs. obese Zucker rats (OZR; control);

  • P < 0.05 vs. LZR [Nω-nitro-l-arginine methyl ester (l-NAME)].