Table 1.

Left ventricular function in four groups of animals that underwent either sham MI or MI and sham RDx or RDx

Sh-ShMI-ShSh-RDxMI-RDx
n117119
Mean arterial pressure, mmHg92 ± 589 ± 572 ± 2*78 ± 5
Heart rate, bpm364 ± 11340 ± 15372 ± 15375 ± 13
LV systolic max, mmHg122 ± 3113 ± 5104 ± 5*107 ± 6
LVEDP, mmHg3.8 ± 0.38.1 ± 1.7*3.9 ± 0.77.1 ± 1.4
LV dP/dtmax, mmHg/s10,395 ± 6506,465 ± 632*8,837 ± 10797,714 ± 845
LV dP/dtmin, mmHg/s−9,247 ± 865−5,365 ± 804*−6,799 ± 544*−6,092 ± 676
τ, ms9.5 ± 1.312.9 ± 1.1*8.4 ± 0.49.0 ± 0.9
Infarct size, % of LV40 ± 337 ± 3
  • Values are expressed as means ± SE. bpm, beats per minute; LV, left ventricle; LVEDP, left ventricular end-diastolic pressure; BW, body weight; dP/dtmax, maximal left ventricular rate of pressure over time; dP/dtmin, minimal left ventricular rate of pressure over time; MI, myocardial infarction; RDx, renal denervation; Sh-Sh, sham myocardial MI+sham RDx; MI-Sh, MI+sham RDx; Sh-RDx, sham MI+RDx; MI-RDx, MI+RDx.

  • * Significant difference from Sh-Sh group, P < 0.05.