Table 2.

Effects of radiation and diabetes on mean abundance of collagen, TG levels, and MMP activity in skeletal muscle of Non-Rad-CTL, Rad-CTL, and Rad-DM rhesus macaques

GroupP Value
Non-Rad-CTLRad-CTLRad-DMOverallRadiation effectDiabetes effect
Collagen IHC, %stained
    Type I5.79 ± 0.724.50 ± 0.344.48 ± 0.830.270.090.50
    Type III3.47 ± 0.584.44 ± 0.593.44 ± 0.610.380.500.46
    Type IV8.78 ± 0.678.29 ± 0.439.86 ± 0.640.190.750.04
MMP9 activity, AU0.90 ± 0.341.35 ± 0.370.74 ± 0.260.390.800.32
Muscle TG, μg/mg protein64.55 ± 12.7a32.12 ± 3.54a90.18 ± 25.19b0.040.870.04
  • Values are means ± SE. MMP9, matrix metalloproteinase 9; AU, arbitrary units. Different superscripted letters (a and b) indicate significant difference between groups (P < 0.05).